Present study reports the phytochemical profiling, antimicrobial, antioxidant, and anticancer activities of Syngonium podophyllum leaf ethyl acetate extract. Dried leaf samples were extracted with ethyl acetate by using soxhlet apparatus. Phytochemical screening revealed the presence of flavonoids, terpenoids, reducing sugars, alkaloids and saponins. Total phenolic and flavonoid contents in extracts were 3.67 ± 0.02 mg propyl galate equivalent and 3.23 ± 0.02 mg quercetin equivalents per gram of sample, respectively. At different concentrations reducing ability of the leaf extract was in the range of 0.170–0.350. The extract accounted for moderate DPPH radical scavenging potential (50 %) and metal ion chelating ability (55 %) at higher concentrations. Test extract provided about 30–36 % protection against peroxidation of membrane lipids in rat tissue homogenate. The extract exhibited 43 % growth inhibition against lung cancer (NCI-H322) and 53 % against breast cancer (T47D) cell lines. In disc diffusion assay extract demonstrated considerable antibacterial activity (ZOI 12–15 mm) against Bacillus cereus (MTCC 6840), Streptococcus mutans (MTCC 497), Proteus vulgaris (MTCC 7299), Salmonella typhi (MTCC 3917), and Bordetella bronchiseptica (MTCC 6838) in comparison with standard antibiotics (ZOI 15–16 mm). The study revealed moderate antioxidant, anticancer and considerable antibacterial activities in S. podophyllum leaf ethyl acetate extract.
National Academy Science Letters – Springer Journals
Published: Mar 5, 2015
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera