Pediatr Surg Int (2018) 34:335–341 DOI 10.1007/s00383-017-4212-2 ORIGINAL ARTICLE Pediatric patients receiving naloxone within 48 h of anesthesia: a case–control study 1 1 1 Vinay K. Donempudi · Juraj Sprung · Toby N. Weingarten Accepted: 5 November 2017 / Published online: 9 November 2017 © Springer-Verlag GmbH Germany, part of Springer Nature 2017 Abstract administrations occurred in a monitored setting implies that Purpose Excessive narcotization in pediatric surgi- at-risk patients had been appropriately identified and kept cal patients has not been well characterized. This report under closer surveillance. describes the use of postoperative naloxone in pediatric patients. Keywords Analgesics · General anesthesia · Methods Pediatric surgical patients from January 1, 2010, Hypoventilation · Narcotic antagonists · Postoperative through June 30, 2016, who underwent general anesthesia complications · Surgery and received naloxone within 48 h postoperatively were identified and matched 1:1 with controls by age, sex, and Abbreviations procedure. Cases and controls underwent retrospective chart ICU Intensive care unit review.IQR Interquartile range Results Forty-seven patients received naloxone, with a rate ME Morphine equivalents of 2.0 (95% CI 1.5–2.7) per 1000 anesthetics. Indications PACU Postanesthesia care unit were respiratory depression (n = 19), facilitating extuba- tion (n = 15), and reversing sedation (n = 13), and 44 cases received naloxone in a monitored environment.
Pediatric Surgery International – Springer Journals
Published: Nov 9, 2017
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