Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum Disorders

Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum... There is growing evidence of altered connectivity in autism spectrum disorders (ASD) between the cerebellum and cortex. Three intrinsic connectivity networks (ICNs) are especially important to cognitive processing in ASD: the default mode network (DMN), executive control network (ECN), and salience networks (SNs). The goal of this study was to compare resting-state functional connectivity between the cerebellum and the DMN, ECN, and SN in ASD and typically developing children (n = 74, ages 7–12 years). Children with ASD showed stronger connectivity between the ventral DMN and left cerebellar lobules I–IV. No meaningful relationships were observed between ICN-cerebellar functional connectivity and ASD symptoms. These results suggest that the cerebellum contributes to altered network connectivity in ASD. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Autism and Developmental Disorders Springer Journals

Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum Disorders

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Publisher
Springer Journals
Copyright
Copyright © 2019 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Psychology; Child and School Psychology; Pediatrics; Neurosciences; Public Health
ISSN
0162-3257
eISSN
1573-3432
DOI
10.1007/s10803-019-04168-w
Publisher site
See Article on Publisher Site

Abstract

There is growing evidence of altered connectivity in autism spectrum disorders (ASD) between the cerebellum and cortex. Three intrinsic connectivity networks (ICNs) are especially important to cognitive processing in ASD: the default mode network (DMN), executive control network (ECN), and salience networks (SNs). The goal of this study was to compare resting-state functional connectivity between the cerebellum and the DMN, ECN, and SN in ASD and typically developing children (n = 74, ages 7–12 years). Children with ASD showed stronger connectivity between the ventral DMN and left cerebellar lobules I–IV. No meaningful relationships were observed between ICN-cerebellar functional connectivity and ASD symptoms. These results suggest that the cerebellum contributes to altered network connectivity in ASD.

Journal

Journal of Autism and Developmental DisordersSpringer Journals

Published: Aug 31, 2019

References

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