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Optimizing locoregional staging in the preoperative setting of resectable esophageal cancer



Surg Endosc (2011) 25:1344–1345 DOI 10.1007/s00464-010-1283-8 Charalambos Batsis • Ioannis Makris Published online: 20 August 2010 Ó Springer Science+Business Media, LLC 2010 As preoperative, also called neoadjuvant, chemoradiotherapy has increasingly been incorporated into clinical practice for the multimodal treatment of resectable esophageal cancer, there is an increased interest in how accurately the clinical stage (cTNM) needs to be predicted before the initiation of neoadjuvant treatment, staging (yTNM), subsequent surgery, and final histopathologic examination of the surgical specimen (pTNM staging). Imaging technology including endoscopic ultrasonography (EUS), positron-emission tomography (PET), and computed tomography (CT) currently is suggested for the preoperative staging of esophageal cancer [1]. But some controversy exists concerning the clinical utility of using of all these imaging tools to improve staging considering predictive accuracy and cost-effectiveness analysis. To evaluate the utility and limitations of EUS, PET, and CT in the pretreatment locoregional staging of resectable esophageal cancer, Choi et al. [2] performed a comparative study published in the June issue of Surgical Endoscopy. For 109 patients, the sensitivity, specificity, and accuracy of tumor depth (T) staging and regional lymph nodal (N) staging for EUS, PET, and CT were compared with the postoperative histopathologic stage (pTNM). Endoscopic ultrasonography was



Surgical EndoscopySpringer Journals

Published: Apr 1, 2011

DOI: 10.1007/s00464-010-1283-8

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