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Purpose of the Review A significant increase in the number, type and availability of new psychoactive substances (NPS) with dissociative and psychedelic potential has occurred worldwide over the last few decades. Psychedelic substances have histori- cally been used in order to achieve altered states of consciousness such as dissociative states. We aimed here at describing both a large number of novel ketamine-like dissociatives and tryptamine/lysergamide/phenethylamine psychedelics available, whilst describing the acute/long-term clinical scenarios most commonly associated with their intake. Recent Findings An updated overview of the clinical and clinical pharmacological issues related to some of the most popular NPS categories has been provided, describing both psychosis and remaining psychopathological issues related to them. Conclusions Although the complex link between NPS and psychiatric illnesses is yet to be fully understood, NPS misuse is now a significant clinical issue and an increasing challenge for clinicians working in both mental health and emergency departments. . . . . . Keywords New psychoactive substances NPS Dissociation Psychedelics Drug-induced psychosis Drug misuse This article is part of the Topical Collection on Dissociation and Addictive Behaviors * Stefania Chiappini Psychopharmacology, Drug Misuse and Novel Psychoactive stefaniachiappini9@gmail.com Substances Research Unit, School of Life and Medical Sciences,
Current Addiction Reports – Springer Journals
Published: Apr 23, 2019
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