Access the full text.
Sign up today, get DeepDyve free for 14 days.
C. Kim, B. Yoon, S. Park, M. Kim, J. Chi (2001)
Acute funisitis of preterm but not term placentas is associated with severe fetal inflammatory response.Human pathology, 32 6
R. Redline, D. Wilson-Costello, M. Hack (2002)
Placental and Other Perinatal Risk Factors for Chronic Lung Disease in Very Low Birth Weight InfantsPediatric Research, 52
M. Adinolfi (1993)
Infectious Diseases in Pregnancy, Cytokines and Neurological Impairment: an HypothesisDevelopmental Medicine & Child Neurology, 35
R. Naeye, M. Maisels, R. Lorenz, J. Botti (1983)
The clinical significance of placental villous edema.Pediatrics, 71 4
A. Leviton, N. Paneth, M. Reuss, M. Susser, E. Allred, O. Dammann, K. Kuban, L. Marter, M. Pagano, T. Hegyi, M. Hiatt, U. Sanocka, F. Shahrivar, M. Abiri, D. Disalvo, P. Doubilet, R. Kairam, E. Kazam, M. Kirpekar, D. Rosenfeld, S. Schonfeld, J. Share, M. Collins, D. Genest, D. Heller, S. Shen‐Schwarz, For Investigators, N. Committee, Ultrasound Committee, Placenta Committee (1999)
Maternal Infection, Fetal Inflammatory Response, and Brain Damage in Very Low Birth Weight InfantsPediatric Research, 46
B. Yoon, R. Romero, Soon-Ha Yang, J. Jun, In-One Kim, J. Choi, H. Syn (1996)
Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia.American journal of obstetrics and gynecology, 174 5
R. Redline, D. Wilson-Costello, E. Borawski, A. Fanaroff, M. Hack (2000)
The Relationship Between Placental and Other Perinatal Risk Factors for Neurologic Impairment in Very Low Birth Weight ChildrenPediatric Research, 47
J. Alexander, L. Gilstrap, S. Cox, D. Mcintire, K. Leveno (1998)
Clinical Chorioamnionitis and the Prognosis for Very Low Birth Weight InfantsObstetrics & Gynecology, 91
A. Lyon (2000)
Chronic lung disease of prematurity. The role of intra-uterine infectionEuropean Journal of Pediatrics, 159
R. Redline, P. Patterson (1994)
Patterns of placental injury. Correlations with gestational age, placental weight, and clinical diagnoses.Archives of pathology & laboratory medicine, 118 7
K. Benirschke, P. Kaufmann (1974)
Pathology of the Human Placenta
Ira Adams-Chapman, Y. Vaucher, R. Bejar, K. Benirschke, R. Baergen, T. Moore (2002)
Maternal Floor Infarction of the Placenta: Association With Central Nervous System Injury and Adverse Neurodevelopmental OutcomeJournal of Perinatology, 22
C. Felice, P. Toti, R. Laurini, M. Stumpo, E. Picciolini, T. Todros, P. Tanganelli, G. Buonocore, R. Bracci (2001)
Early neonatal brain injury in histologic chorioamnionitis.The Journal of pediatrics, 138 1
Watts Dh, M. Krohn, S. Hillier, D. Eschenbach (1992)
The association of occult amniotic fluid infection with gestational age and neonatal outcome among women in preterm labor.Obstetrics and gynecology, 79 3
S. Jacques, F. Qureshi (1998)
Chronic chorioamnionitis: a clinicopathologic and immunohistochemical study.Human pathology, 29 12
F. Arias, A. Victoria, K. Cho, F. Kraus (1997)
Placental Histology and Clinical Characteristics of Patients With Preterm Premature Rupture of MembranesObstetrics & Gynecology, 89
Frederick Kraus, Frederick Kraus, Viviana Acheen, Viviana Acheen (1999)
Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy.Human pathology, 30 7
M. Tauscher, D. Berg, M. Brockmann, S. Seidenspinner, Christian Speer, P. Groneck (2003)
Association of Histologic Chorioamnionitis, Increased Levels of Cord Blood Cytokines, and Intracerebral Hemorrhage in Preterm NeonatesNeonatology, 83
T. Khong, R. Bendon, F. Qureshi, R. Redline, S. Gould, T. Stallmach, J. Lipsett, A. Staples (2000)
Chronic deciduitis in the placental basal plate: definition and interobserver reliability.Human pathology, 31 3
R. Vigneswaran (2000)
Infection and preterm birth: Evidence of a common causal relationship with bronchopulmonary dysplasia and cerebral palsyJournal of Paediatrics and Child Health, 36
O. Dammann, A. Leviton (1997)
Maternal Intrauterine Infection, Cytokines, and Brain Damage in the Preterm NewbornPediatric Research, 42
D. Murphy, A.M Johnson, S. Sellers, I.Z MacKenzie (1995)
Case-control study of antenatal and intrapartum risk factors for cerebral palsy in very preterm singleton babiesThe Lancet, 346
P. Pacora, T. Chaiworapongsa, E. Maymon, Y. Kim, R. Gomez, B. Yoon, F. Ghezzi, S. Berry, Faisal Qureshi, S. Jacques, J. Kim, N. Kadar, R. Romero (2002)
Funisitis and chorionic vasculitis: the histological counterpart of the fetal inflammatory response syndromeThe Journal of Maternal-Fetal & Neonatal Medicine, 11
S. Dexter, M. Malee, J. Hogan, M. Carpenter, B. Bohr (2000)
Outcome of Very Low Birth Weight Infants With Histopathologic ChorioamnionitisObstetrics & Gynecology, 96
U. Verma, N. Tejani, Susan Klein, M. Reale, D. Beneck, R. Figueroa, P. Visintainer (1997)
Obstetric antecedents of intraventricular hemorrhage and periventricular leukomalacia in the low-birth-weight neonate.American journal of obstetrics and gynecology, 176 2
M. Hallman (1999)
Cytokines, Pulmonary Surfactant and Consequences of Intrauterine InfectionNeonatology, 76
M. Grafe (1993)
The Correlation of Prenatal Brain Damage with Placental PathologyJournal of Neuropathology and Experimental Neurology, 53
N. Ambalavanan, K. Nelson, G. Alexander, Susan Johnson, F. Biasini, W. Carlo (2000)
Prediction of Neurologic Morbidity in Extremely Low Birth Weight InfantsJournal of Perinatology, 20
C. Langston, C. Kaplan, Trevor Macpherson, E. Manci, K. Peevy, B. Clark, C. Murtagh, S. Cox, G. Glenn (1997)
Practice guideline for examination of the placenta: developed by the Placental Pathology Practice Guideline Development Task Force of the College of American Pathologists.Archives of pathology & laboratory medicine, 121 5
B. Yoon, J. Jun, R. Romero, K. Park, R. Gomez, J. Choi, In-One Kim (1997)
Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1β, and tumor necrosis factor-α), neonatal brain white matter lesions, and cerebral palsyAmerican Journal of Obstetrics and Gynecology, 177
S. Dexter, M. Malee, H. Pinar, J. Hogan, M. Carpenter, B. Vohr (1999)
Influence of chorioamnionitis on developmental outcome in very low birth weight infants.Obstetrics and gynecology, 94 2
C. Salafia, A. Vintzileos (1990)
Why all placentas should be examined by a pathologist in 1990.American journal of obstetrics and gynecology, 163 4 Pt 1
K. Kumazaki, M. Nakayama, Yutaka Sumida, K. Ozono, S. Mushiake, N. Suehara, Y. Wada, M. Fujimura (2002)
Placental features in preterm infants with periventricular leukomalacia.Pediatrics, 109 4
R. Redline, Deanne Wilson-Costello, E. Borawski, A. Fanaroff, M. Hack (1998)
Placental lesions associated with neurologic impairment and cerebral palsy in very low-birth-weight infants.Archives of pathology & laboratory medicine, 122 12
Objective : To investigate the association between gestational age, placental pathology and outcome among preterm births. Methods : Medical records and placental pathology results of 165 preterm infants (gestational age ≤34 weeks) were used to analyze the development of intraventricular hemorrhage (IVH), bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), patent ductus arteriosus (PDA) and sepsis, in association with placental findings in the gestational age categories of 22–27 (n=71) and 28–33 (n=93) weeks. Results : Significant differences were found in placental findings based on gestational age and neonatal morbidity. Lower gestational age was associated with increased infection-related lesions such as chorionic vasculitis (47.9%, P<0.001) and acute chorioamnionitis (67.6%, P<0.001). Placental lesions reflecting disturbances of fetal-placental blood flow (infarction, chorionic plate thrombi and basal perivillous fibrin) were predominantly seen in the 28–33 week gestational age category (P<0.05–0.01). Despite the high prevalence of chorioamnionitis (38.8%), no significant association was found between this lesion and the tested preterm morbidity after controlling for gestational age. Only, villous edema and chorionic vasculitis were identified as independent predictors for the development of IVH (49.2%, OR A 2.57, 95% CI 1.01, 6.58 and 39.3%, OR A 1.95, 95% CI 1.01, 4.21, respectively). Conclusion : Villous edema and chorionic vasculitis are significant risk factors for the development of the IVH among neonates born at gestational age ≤34 weeks.
Indian Journal of Pediatrics – Springer Journals
Published: Jan 1, 2006
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.