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Navigating the kinome

Navigating the kinome Assisted by 3,800 chemical bioactivities, a bioinformatic analysis explores the inter-relatedness of over 170 kinases and generates a kinase interaction map based on sequence and ligand-binding activity that challenges the robustness of drug interaction networks.[Figure not available: see fulltext.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Chemical Biology Springer Journals

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References (19)

Publisher
Springer Journals
Copyright
Copyright © 2011 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
Subject
Chemistry; Chemistry/Food Science, general; Biochemical Engineering; Biochemistry, general; Cell Biology; Bioorganic Chemistry
ISSN
1552-4450
eISSN
1552-4469
DOI
10.1038/nchembio.530
Publisher site
See Article on Publisher Site

Abstract

Assisted by 3,800 chemical bioactivities, a bioinformatic analysis explores the inter-relatedness of over 170 kinases and generates a kinase interaction map based on sequence and ligand-binding activity that challenges the robustness of drug interaction networks.[Figure not available: see fulltext.]

Journal

Nature Chemical BiologySpringer Journals

Published: Feb 20, 2011

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