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- Publisher
- Springer India
- Copyright
- © Springer India 2014
- ISBN
- 978-81-322-1912-5
- Pages
- 49 –72
- DOI
- 10.1007/978-81-322-1913-2_4
- Publisher site
- See Chapter on Publisher Site
Abstract
[Surface Plasmon Resonance (SPR)-based biosensing systems have become very popular among biologists and biochemists due to their ability to sense biomolecular interaction kinetics. It can be easily surmised that such systems may be of great use in diagnostic applications as well. However, the principal impediment to wide-scale deployment of these devices is the cost of the instrument. This effort to develop a low cost, widely deployable instrument was born out of a desire to initially popularize this instrument and technique among colleges and universities with budget constraints and move toward developing diagnostic applications on this platform. A low-cost device with significant sensitivity was developed, and this chapter describes the development on this front.]
Published: May 22, 2014
Keywords: Surface plasmon resonance; Biosensor; Biomolecular interaction; Immobilization of antibodies; Optical detection