This study compared heartburn severity, numberof episodes, and changes in esophageal pH induced bythree meals. Symptomatic volunteers consumed thefollowing on different occasions: McDonald's Quarter Pounder, french fries, and chocolate shake;McDonald's Sausage Biscuit with Egg, cheese, raw onion,and chocolate milk; and Wendy's Chili and red wine.Increases in reflux episodes over baseline for the hamburger, sausage biscuit, and chili mealswere 28.8 ± 5.7, 36 ± 5.5 and 43.7± 8.8, respectively. The sausage biscuit andchili increased reflux compared to the hamburger (P <0.05), but the chili did not differ statistically from thesausage biscuit meal. Onset and peak heartburn for thehamburger, sausage biscuit, and chili meals were 45 and90, 30 and 120, and 15 and 150 min, respectively. Despite lower fat content, chili and red winepromoted more reflux and heartburn pain than the othermeals, demonstrating the importance of meal selection inprovocative meal studies.
Digestive Diseases and Sciences – Springer Journals
Published: Oct 3, 2004
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