Mammalian Genome 9, 590–592 (1998). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1998 Male sex determination in the spiny rat Tokudaia osimensis (Rodentia: Muridae) is not Sry dependent 1 2 3 1 2 Ste ´phan Soullier, Catherine Hanni, Franc ¸ois Catzeflis, Philippe Berta, Vincent Laudet Institut de Ge ´ne ´tique Humaine, UPR 1142 CNRS, 1919 Route de Mende, 34293 Montpellier cedex 5, France Institut de Biologie de Lille, Institut Pasteur, URA 1160 CNRS, 1 rue Calmette, 59021 Lille cedex, France Institut des Sciences de l’Evolution, UMR 5554 CNRS, Universite ´ de Montpellier II, Place Euge `ne Bataillon, 34095 Montpellier cedex, France Received: 24 November 1997 / Accepted: 21 February 1998 In mammals, gender follows from the development of the two transcription factors Sox3 and Zfx (Fig. 1 and data not shown). embryonic gonads as testis or ovaries and is under genetic control. These results, obtained with autosomal and X Chr encoded genes, In males, testis development is dependent on the inheritance of the clearly demonstrate that our conditions allow the detection of Y Chromosome-encoded Sry gene. It is believed, as a result of single-copy genes. Taken together, these data indicate that the Sry transgenic experiments, that Sry is
Mammalian Genome – Springer Journals
Published: Jul 1, 1998
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