Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/springer-journals/lex-and-related-structures-as-adhesion-molecules-S7ZCegscCZ
References (29)
-
N. Kojima, K. Handa, W. Newman, S. Hakomori (1992)
Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cells.Biochemical and biophysical research communications, 182 3
-
M. Stroud, S. Levery, M. Salyan, C. Roberts, S. Hakomori (1992)
Extended type-1 chain glycosphingolipid antigens. Isolation and characterization of trifucosyl-Leb antigen (III4V4VI2Fuc3Lc6).European journal of biochemistry, 203 3
-
Hirofumi Okoshi, Sen-itiroh Hakomori, Mohammad Nisar, Qinghong Zhou, Satoshi Kimura, Kazuhiro Tashiro, Yasuyuki Igarashi (1991)
Cell membrane signaling as target in cancer therapy. II: Inhibitory effect of N,N,N-trimethylsphingosine on metastatic potential of murine B16 melanoma cell line through blocking of tumor cell-dependent platelet aggregation.Cancer research, 51 22
-
D. Solter, B. Knowles (1978)
Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1).Proceedings of the National Academy of Sciences of the United States of America, 75 11
-
E. Berg, Robinson Kim, O. Månsson, E. Butcher, J. Magnani (1991)
A carbohydrate domain common to both sialyl Le(a) and sialyl Le(X) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1.The Journal of biological chemistry, 266 23
-
K. Abe, J. Mckibbin, S. Hakomori (1983)
The monoclonal antibody directed to difucosylated type 2 chain (Fuc alpha 1 leads to 2Gal beta 1 leads to 4[Fuc alpha 1 leads to 3]GlcNAc; Y Determinant).The Journal of biological chemistry, 258 19
-
Y. Fukushi, E. Nudelman, S. Levery, S. Hakomori, H. Rauvala (1984)
Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6).The Journal of biological chemistry, 259 16
-
K. Lloyd, G. Larson, N. Strömberg, J. Thurin, K. Karlsson (2004)
Mouse monoclonal antibody F-3 recognizes the difucosyl type-2 blood group structureImmunogenetics, 17
-
S. Hakomori (1989)
Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens.Advances in cancer research, 52
-
K. Abe, J. M. McKibbin, S. Hakomori (1983)
The monoclonal antibody directed to difucosylated type 2 chain (Fucα1→2Galβ1→4[Fucα1→3]GlcNAc; Y determinant)J. Biol. Chem., 258
-
A. Takada, K. Ohmori, N. Takahashi, K. Tsuyuoka, A. Yago, K. Zenita, A. Hasegawa, R. Kannagi (1991)
Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl LewisA. Biochem. Biophys. Res. Commun., 179
-
M. Phillips, Edward Nudelman, F. Gaeta, M. Perez, A. Singhal, Sen-itiroh Hakomori, James Paulson (1990)
ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex.Science, 250 4984
-
A. Brown, Ten Feizi, H. Gooi, M. Embleton, J. Picard, Robert Baldwin (1983)
A monoclonal antibody against human colonic adenoma recognizes difucosylated Type-2-blood-group chainsBioscience Reports, 3
-
M. Polley, M. Phillips, E. Wayner, Edward NUDELMANt, Anil SINGHALt, S. Hakomori, J. Paulson (1991)
CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x.Proceedings of the National Academy of Sciences of the United States of America, 88 14
-
T. Kaizu, S. Levery, E. Nudelman, R. Stenkamp, S. Hakomori (1986)
Novel fucolipids of human adenocarcinoma: monoclonal antibody specific for trifucosyl Ley (III3FucV3FucVI2FucnLc6) and a possible three-dimensional epitope structure.The Journal of biological chemistry, 261 24
-
S. Hakomori, E. Nudelman, S. Levery, R. Kannagi (1984)
Novel fucolipids accumulating in human adenocarcinoma. I. Glycolipids with di- or trifucosylated type 2 chain.The Journal of biological chemistry, 259 7
-
K. Handa, E. Nudelman, M. Stroud, T. Shiozawa, S. Hakomori (1991)
Selectin GMP-140 (CD62; PADGEM) binds to sialosyl-Le(a) and sialosyl-Le(x), and sulfated glycans modulate this binding.Biochemical and biophysical research communications, 181 3
-
Akiko Takada, Katsuyuki Ohmori, Naofumi Takahashi, K. Tsuyuoka, Akihiro Yago, K. Zenita, A. Hasegawa, Reiji Kannagi (1991)
Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl Lewis A.Biochemical and biophysical research communications, 179 2
-
H. Yang, S. Hakomori (1971)
A sphingolipid having a novel type of ceramide and lacto-N-fucopentaose 3.The Journal of biological chemistry, 246 5
-
H. Gooi, Ten Feizi, A. Kapadia, Barbara Knowles, Davor Solter, M. Evans (1981)
Stage-specific embryonic antigen involves αl→ 3 fucosylated type 2 blood group chainsNature, 292
-
M. Stroud, S. Levery, E. Nudelman, M. Salyan, J. Towell, C. Roberts, M. Watanabe, S. Hakomori (1991)
Extended type 1 chain glycosphingolipids: dimeric Lea (III4V4Fuc2Lc6) as human tumor-associated antigen.The Journal of biological chemistry, 266 13
-
Ivan Eggens, B. Fenderson, T. Toyokuni, B. Dean, M. Stroud, Sen-itiroh Hakomori (1989)
Specific interaction between Lex and Lex determinants. A possible basis for cell recognition in preimplantation embryos and in embryonal carcinoma cells.The Journal of biological chemistry, 264 16
-
Masahiko Watanabe, T. Ohishi, M. Kuzuoka, E. Nudelman, M. Stroud, T. Kubota, S. Kodaira, O. Abe, S. Hirohashi, Y. Shimosato, S. Hakomori (1991)
In vitro and in vivo antitumor effects of murine monoclonal antibody NCC-ST-421 reacting with dimeric Lea (Lea/Lea)epitopeCancer Research, 51
-
B. A. Fenderson, N. Kojima, M. R. Stroud, Z. Zhu, S. Hakomori (1991)
Specific interaction between Ley and H as a possible basis for trophectoderm-endometrium recognition during implantation [abstract 8.5]Glycoconjugate J., 8
-
S. Hakomori, S. Hakomori, E. Nudelman, E. Nudelman, S. Levery, S. Levery, D. Solter, B. Knowles (1981)
The hapten structure of a developmentally regulated glycolipid antigen (SSEA-1) isolated from human erythrocytes and adenocarcinoma: a preliminary note.Biochemical and biophysical research communications, 100 4
-
S. Hakomori (1991)
Carbohydrate-carbohydrate interaction as an initial step in cell recognitionPure and Applied Chemistry, 63
-
B. Fenderson, U. Zehavi, S. Hakomori (1984)
A multivalent lacto-N-fucopentaose III-lysyllysine conjugate decompacts preimplantation mouse embryos, while the free oligosaccharide is ineffectiveThe Journal of Experimental Medicine, 160
-
S. Hakomori (1991)
New directions in cancer therapy based on aberrant expression of glycosphingolipids: anti-adhesion and ortho-signaling therapy.Cancer cells, 3 12
-
T. Springer, L. Lasky (1991)
Sticky sugars for selectinsNature, 349
- Publisher
- Springer Journals
- Copyright
- Copyright
- Subject
- Life Sciences; Cell Biology; Biomedicine, general; Developmental Biology
- ISSN
- 1567-2379
- eISSN
- 1573-6865
- DOI
- 10.1007/BF01046348
- Publisher site
- See Article on Publisher Site
Abstract
Lex (α1→3 fucosylated type 2 chain) functions as an adhesion molecule capable of Ca2+-mediated homotypic binding. Cells with high surface expression of Lex therefore exhibit strong self-aggregation (based on Lex-Lex interaction) in the presence of Ca2+. In this review, I have summarized several lines of supporting data for this concept, and the role of Lex-Lex interaction in the process of embryo compaction and autoaggregation of F9 teratocarcinoma cells. In general, cell adhesion events based on Lex-Lex interaction may be followed and reinforced by integrin- or Ig receptor-based adhesion systems.
Journal
Journal of Molecular Histology – Springer Journals
Published: Jan 10, 2005