Latex-fruit syndrome

Latex-fruit syndrome Natural rubber latex immunoglobulin E-mediated hypersensitivity is probably one of the most relevant challenges that has been faced in the treatment of allergies during recent years. Additionally, allergen cross-reactivity has arisen as another very important problem, in the difficulty in diagnosing it and in its clinical implications. It is clear that some latex allergens cross-react with plant-derived food allergens, the so-called latex-fruit syndrome, with evident clinical consequences. Although the foods most frequently involved are banana, avocado, kiwi, and chestnut, several others are also implicated. Investigations point to a group of defense-related plant proteins, class I chitinases, which cross-react with a major latex allergen, hevein, as the panallergens responsible for the syndrome. This review focuses on our current understanding of the latex-fruit syndrome. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Allergy and Asthma Reports Springer Journals

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Publisher
Springer Journals
Copyright
Copyright © 2003 by Current Science Inc.
ISSN
1529-7322
eISSN
1534-6315
DOI
10.1007/s11882-003-0012-y
Publisher site
See Article on Publisher Site

Abstract

Natural rubber latex immunoglobulin E-mediated hypersensitivity is probably one of the most relevant challenges that has been faced in the treatment of allergies during recent years. Additionally, allergen cross-reactivity has arisen as another very important problem, in the difficulty in diagnosing it and in its clinical implications. It is clear that some latex allergens cross-react with plant-derived food allergens, the so-called latex-fruit syndrome, with evident clinical consequences. Although the foods most frequently involved are banana, avocado, kiwi, and chestnut, several others are also implicated. Investigations point to a group of defense-related plant proteins, class I chitinases, which cross-react with a major latex allergen, hevein, as the panallergens responsible for the syndrome. This review focuses on our current understanding of the latex-fruit syndrome.

Journal

Current Allergy and Asthma ReportsSpringer Journals

Published: May 27, 2003

References

  • The spectrum of immunologic sensitization in latex allergy
    Kurup, VP; Fink, JN
  • Associated sensitization to latex and chestnut
    Añíbarro, B; García-Ara, MC; Pascual, C
  • Latex allergy can induce clinical reactions to specific foods
    Beezhold, DH; Sussman, GL; Liss, GM; Chang, NS
  • "Latex-fruit syndrome": frequency of cross-reacting IgE antibodies
    Brehler, R; Theissen, U; Mohr, C; Luger, T
  • Avocado hypersensitivity
    Blanco, C; Carrillo, T; Castillo, R
  • Latex allergy in fruit-allergic patients
    García, JC; Moyano, JC; Alvarez, M; Bellido, J
  • Allergic sensitization and clinical reactions to latex, food and pollen in adult patients
    Levy, DA; Mounedji, N; Noirot, C; Leynadier, F
  • IgE reactivity to patatin-like latex allergen, Hev b 7, and to patatin of potato tuber, Sol t 1, in adults and children allergic to natural rubber latex
    Seppala, U; Palosuo, T; Seppala, U
  • What is the role of the hevein-like domain of fruit class I chitinases in their allergenic capacity?
    Diaz-Perales, A; Sánchez-Monge, R; Blanco, C

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