Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

IVIM DW-MRI of autoimmune pancreatitis: therapy monitoring and differentiation from pancreatic cancer

IVIM DW-MRI of autoimmune pancreatitis: therapy monitoring and differentiation from pancreatic... Objectives To evaluate IVIM DW-MRI for changes in IVIM- during steroid treatment and pancreatic cancer suggest that derived parameters during steroid treatment of autoimmune IVIM-diffusion MRI could serve as imaging biomarker during pancreatitis (AIP) and for the differentiation from pancreatic treatment in AIP-patients and as a helpful tool for differentia- cancer (PC). tion between PC and AIP. Methods Fifteen AIP-patients, 11 healthy patients and 20 PC- Key Points patients were examined with DWI-MRI using eight b-values � MRI is used for follow-up examinations during therapy in (50, 100, 150, 200, 300, 400, 600, 800). 12 AIP-patients AIP-patients underwent follow-up examinations during treatment. IVIM- � IVIM-DWI-MRI offers parameters which reflect perfusion parameters and ADC -values were tested for significant dif- and true diffusion ferences and an ROC analysis was performed. � IVIM-parameters are helpful for differentiation between AIP Results The perfusion fraction f was significantly lower in and pancreatic cancer patients with AIP at the time of diagnosis (10.5±4.3 %) than � IVIM-parameters could serve as an imaging biomarker dur- in patients without AIP (20.7±4.3 %). In AIP follow-up, f ing steroid treatment increased significantly to 17.1±7.0 % in the first and 21.0± . . . 4.1 % in the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Radiology Springer Journals

IVIM DW-MRI of autoimmune pancreatitis: therapy monitoring and differentiation from pancreatic cancer

Download PDF
8 pages

Loading next page...
 
/lp/springer-journals/ivim-dw-mri-of-autoimmune-pancreatitis-therapy-monitoring-and-kgc84cBTre

References (23)

Publisher
Springer Journals
Copyright
Copyright © 2015 by European Society of Radiology
Subject
Medicine & Public Health; Imaging / Radiology; Diagnostic Radiology; Interventional Radiology; Neuroradiology; Ultrasound; Internal Medicine
ISSN
0938-7994
eISSN
1432-1084
DOI
10.1007/s00330-015-4041-4
pmid
26449558
Publisher site
See Article on Publisher Site

Abstract

Objectives To evaluate IVIM DW-MRI for changes in IVIM- during steroid treatment and pancreatic cancer suggest that derived parameters during steroid treatment of autoimmune IVIM-diffusion MRI could serve as imaging biomarker during pancreatitis (AIP) and for the differentiation from pancreatic treatment in AIP-patients and as a helpful tool for differentia- cancer (PC). tion between PC and AIP. Methods Fifteen AIP-patients, 11 healthy patients and 20 PC- Key Points patients were examined with DWI-MRI using eight b-values � MRI is used for follow-up examinations during therapy in (50, 100, 150, 200, 300, 400, 600, 800). 12 AIP-patients AIP-patients underwent follow-up examinations during treatment. IVIM- � IVIM-DWI-MRI offers parameters which reflect perfusion parameters and ADC -values were tested for significant dif- and true diffusion ferences and an ROC analysis was performed. � IVIM-parameters are helpful for differentiation between AIP Results The perfusion fraction f was significantly lower in and pancreatic cancer patients with AIP at the time of diagnosis (10.5±4.3 %) than � IVIM-parameters could serve as an imaging biomarker dur- in patients without AIP (20.7±4.3 %). In AIP follow-up, f ing steroid treatment increased significantly to 17.1±7.0 % in the first and 21.0± . . . 4.1 % in the

Journal

European Radiology – Springer Journals

Published: Oct 8, 2015

There are no references for this article.