Sox genes encode a family of transcription factors, which are characterized by the conserved HMG domain and are involved in a diverse range of developmental processes. Using degenerate primer PCR, seven different sequences encoding the HMG domains of Sox1, Sox9 and Sox11b were cloned and sequenced from genomic DNA in the red crucian carp (Carassius carassius, red variety). In the case of Sox1 and Sox11b, we found evidence of gene duplication. In the phylogenetic tree, two paralogs of Sox11b (Sox11b1 and Sox11b2) fit within the clade of Sox11, especially in the Sox11 b subfamily, not in the Sox11a subfamily. Three Sox1 sequences (Sox1-1, Sox1-2, and Sox1-3), which shared the same amino acid sequence, were identified in the red crucian carp. At the nucleotide level, Sox1-1 shared the highest sequence similarity to the zebrafish Sox1a, and Sox1-2 and Sox1-3 showed the highest similarity to the zebrafish Sox1b. The phylogenetic tree clearly demonstrated that the red crucian carp Sox1-1 clustered together with the zebrafish Sox1a, and the red crucian carp Sox1-2 and Sox1-3, with the zebrafish Sox1b. The result suggested that the red crucian carp Sox1-1, Sox1-2 and Sox1-3 resulted from duplication of the Sox1 gene rather than polymorphisms of the same gene.
Russian Journal of Genetics – Springer Journals
Published: Feb 15, 2009
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera