Ann Surg Oncol (2019) 26:8–9 https://doi.org/10.1245/s10434-018-7067-4 EDITORIAL – MELANOMA Isolated Limb Infusion and Isolated Limb Perfusion for Melanoma: Can the Outcomes of these Procedures be Compared? 1,2 1,3,4 Hidde M. Kroon, MD, PhD and John F. Thompson, MD, FRACS, FACS 1 2 Melanoma Institute Australia, The University of Sydney, North Sydney, NSW,Australia; Department of General Surgery, The University of Adelaide, Royal Adelaide Hospital, Adelaide, SA, Australia; Discipline of Surgery, The University of Sydney, Sydney, NSW, Australia; Department of Melanoma and Surgical Oncology, Royal Prince Alfred Hospital, Sydney, NSW, Australia When bulky or numerous local melanoma recurrences or locally recurrent or in-transit metastatic melanoma in-transit melanoma metastases develop in a limb, simple involving a limb. Furthermore, both procedures have local treatment modalities such as excision, cryotherapy, acceptable, usually minor, locoregional postoperative tox- laser ablation, or intralesional injection with Rose Bengal icity with a short hospital stay. Overall responses of (PV-10) or talimogene laherparepvec (T-VEC) are likely to 64–96% can be achieved after ILP, while, in large ILI be ineffective or simply not possible. However, achieving series, overall response rates of 43–84% have been repor- adequate disease control is important in these patients as ted, with somewhat lower complete response rates
Annals of Surgical Oncology – Springer Journals
Published: Nov 21, 2018
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