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of Shine–Dalgarno- independent translation, which was functionally confirmed by reporter protein expression in Escherichia coli. THERAPY In vivo genome editing restores haemostasis in a mouse model ...
S.Y. Bhagwat A.S. Malani N. Anguela X.M. Sharma R. Ivanciu L.et al. In vivo genome editing restores haemostasis in a mouse model of haemophilia Nature 2011 475 217 221 Google Scholar Crossref Search ADS ...
in the iPSC genome by the gene editing system and the selection of the p53 pathway inactivated cells48,51 need to be carefully addressed before moving forward to clinical trials. We used two HA mouse models ...
, T. , Wong , S.Y. , Bhagwat , A.S. , Malani , N. , Anguela , X.M. , Sharma , R. , Ivanciu , L. et al. ( 2011 ) In vivo genome editing restores haemostasis in a mouse model of haemophilia . Nature , 475 ...
, Ivanciu L , Murphy SL , Finn JD , Khazi FR , Zhou S , Paschon DE , Rebar EJ , Bushman FD , Gregory PD , Holmes MC , High KA . In vivo genome editing restores haemostasis in a mouse model of haemophilia ...
(Critchley et al., 2003; Evans and Salamonsen, 2014) and in mouse models of decidualization and menstruation (Cheng et al., 2007; Wang et al., 2013; Xu et al., 2013). Molecular pathways identified include ...
to obtain information more easily and less invasively than from in vivo experiments. However, for studies of exosomal communication, advanced cell models are needed that can compare the use of single cell ...
and caspase-1 in coronary arteritis has been established in a mouse model of KD [175]. Genetic and pharmacological evidence supports the issue that IL-1β maturation and secretion are dependent upon the non ...
of fluids, nutrients, and metabolites, and is critical to haemostasis and vascular health. In healthy arteries, endothelial cells (ECs) exist in a quiescent state that is maintained by laminar blood,1,2 ...
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