RESEARCH HIGHLIGHTS RESEARCH HIGHLIGHTS ©American College of Medical Genetics and Genomics ©American College of Medical Genetics Parents should know “savior baby” not First diagnosis of Duchenne muscular realistic in most cases dystrophy via a noninvasive prenatal test see page 935 see page 889 When a child is diag- A research nosed with Fanconi team based anemia (FA), a rare in Shanghai, genetic syndrome that China, has for results in bone mar- the first time row failure and a pre- su c c e ss f u l l y disposition to cancer, diagnosed the the only option for most com- treatment has been a mon form of genetically matched muscular dys- stem cell transplant. trophy using When neither parent n o ni n v a si v e is a genetic match, prenatal test- some families opt to try to conceive a “savior” sibling using ing (NIPT). in vitro fertilization (IVF) of a genetically matched embryo. Duchenne muscular dystrophy (DMD) is inherited via the But little information about the chances of success using this X chromosome and affects 1 in 3,600 to 6,000 boys. The re - technique has been available. Now a research team from Barce- searchers used a technique they developed to recover, in a lona, Spain, reports only one baby born ae ft r 38 IVF attempts single step, the fetal genotype and both parental sequences by seven families over 11 years. To avoid bias, the researchers from DNA in maternal blood plasma. Using this approach, followed...