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Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task

Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial... α7 nicotinic receptor knockout mice are impaired in performance of the 5-CSRTT, suggesting a possible role for α7 receptors in attentional processing. However, identification of a protocol for assessing attention-enhancing effects of nicotine in mice may require further modifications of test procedures or the use of different strains of animal. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychopharmacology Springer Journals

Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task

Psychopharmacology , Volume 189 (2) – Dec 1, 2006

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References (45)

Publisher
Springer Journals
Copyright
Copyright © 2006 by Springer-Verlag
Subject
Biomedicine; Psychiatry ; Pharmacology/Toxicology
ISSN
0033-3158
eISSN
1432-2072
DOI
10.1007/s00213-006-0549-2
pmid
17019565
Publisher site
See Article on Publisher Site

Abstract

α7 nicotinic receptor knockout mice are impaired in performance of the 5-CSRTT, suggesting a possible role for α7 receptors in attentional processing. However, identification of a protocol for assessing attention-enhancing effects of nicotine in mice may require further modifications of test procedures or the use of different strains of animal.

Journal

PsychopharmacologySpringer Journals

Published: Dec 1, 2006

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