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How Do Fatty Acids Cause Allosteric Binding of Drugs to Human Serum Albumin?

How Do Fatty Acids Cause Allosteric Binding of Drugs to Human Serum Albumin? Purpose. This study was undertaken to investigate how fatty acids cause the allosteric binding of drugs to human serum albumin (HSA). The influence of fatty acids on the binding of ketoprofen (KP), an NSAID, to HSA was examined by using a photoaffinity labeling technique. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pharmaceutical Research Springer Journals

How Do Fatty Acids Cause Allosteric Binding of Drugs to Human Serum Albumin?

Pharmaceutical Research , Volume 19 (10) – Oct 10, 2004

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References (25)

Publisher
Springer Journals
Copyright
Copyright © 2002 by Plenum Publishing Corporation
Subject
Biomedicine; Pharmacology/Toxicology; Pharmacy; Biochemistry, general; Medical Law; Biomedical Engineering
ISSN
0724-8741
eISSN
1573-904X
DOI
10.1023/A:1020496314081
Publisher site
See Article on Publisher Site

Abstract

Purpose. This study was undertaken to investigate how fatty acids cause the allosteric binding of drugs to human serum albumin (HSA). The influence of fatty acids on the binding of ketoprofen (KP), an NSAID, to HSA was examined by using a photoaffinity labeling technique.

Journal

Pharmaceutical ResearchSpringer Journals

Published: Oct 10, 2004

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