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GLUT2 protein at the rat proximal tubule brush border membrane correlates with protein kinase C (PKC)-βl and plasma glucose concentration

GLUT2 protein at the rat proximal tubule brush border membrane correlates with protein kinase C... Enhanced GLUT2-mediated glucose transport across the proximal tubule BBM during diabetic hyperglycaemia is closely associated with increased PKC-βI. Thus, altered levels of GLUT2 and PKC-βI proteins in the BBM may be important factors in the pathogenic processes underlying diabetic renal injury. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Diabetologia Springer Journals

GLUT2 protein at the rat proximal tubule brush border membrane correlates with protein kinase C (PKC)-βl and plasma glucose concentration

Diabetologia , Volume 50 (10) – Oct 1, 2007

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References (56)

Publisher
Springer Journals
Copyright
Copyright © 2007 by Springer-Verlag
Subject
Medicine & Public Health; Human Physiology ; Metabolic Diseases ; Internal Medicine
ISSN
0012-186X
eISSN
1432-0428
DOI
10.1007/s00125-007-0778-x
pmid
17694297
Publisher site
See Article on Publisher Site

Abstract

Enhanced GLUT2-mediated glucose transport across the proximal tubule BBM during diabetic hyperglycaemia is closely associated with increased PKC-βI. Thus, altered levels of GLUT2 and PKC-βI proteins in the BBM may be important factors in the pathogenic processes underlying diabetic renal injury.

Journal

DiabetologiaSpringer Journals

Published: Oct 1, 2007

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