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Genetic and Neuroimaging Features of Personality Disorders: State of the Art

Genetic and Neuroimaging Features of Personality Disorders: State of the Art Personality disorders often act as a common denominator for many psychiatric problems, and studies on personality disorders contribute to the etiopathology, diagnosis, and treatment of many mental disorders. In recent years, increasing evidence from various studies has shown distinctive features of personality disorders, and that from genetic and neuroimaging studies has been especially valuable. Genetic studies primarily target the genes encoding neurotransmitters and enzymes in the serotoninergic and dopaminergic systems, and neuroimaging studies mainly focus on the frontal and temporal lobes as well as the limbic-paralimbic system in patients with personality disorders. Although some studies have suffered due to unclear diagnoses of personality disorders and some have included few patients for a given personality disorder, great opportunities remain for investigators to launch new ideas and technologies in the field. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neuroscience Bulletin Springer Journals

Genetic and Neuroimaging Features of Personality Disorders: State of the Art

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Publisher
Springer Journals
Copyright
Copyright © 2016 by Shanghai Institutes for Biological Sciences, CAS and Springer Science+Business Media Singapore
Subject
Biomedicine; Neurosciences; Human Physiology; Anesthesiology; Anatomy; Neurology; Pain Medicine
ISSN
1673-7067
eISSN
1995-8218
DOI
10.1007/s12264-016-0027-8
pmid
27037690
Publisher site
See Article on Publisher Site

Abstract

Personality disorders often act as a common denominator for many psychiatric problems, and studies on personality disorders contribute to the etiopathology, diagnosis, and treatment of many mental disorders. In recent years, increasing evidence from various studies has shown distinctive features of personality disorders, and that from genetic and neuroimaging studies has been especially valuable. Genetic studies primarily target the genes encoding neurotransmitters and enzymes in the serotoninergic and dopaminergic systems, and neuroimaging studies mainly focus on the frontal and temporal lobes as well as the limbic-paralimbic system in patients with personality disorders. Although some studies have suffered due to unclear diagnoses of personality disorders and some have included few patients for a given personality disorder, great opportunities remain for investigators to launch new ideas and technologies in the field.

Journal

Neuroscience Bulletin – Springer Journals

Published: Apr 1, 2016

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  • Identifying individuals with antisocial personality disorder using resting-state FMRI
    Tang, Y; Jiang, W; Liao, J; Wang, W; Luo, A
  • Borderline personality disorder in young people and the prospects for prevention and early intervention
    Chanen, AM; Jovev, M; McCutcheon, LK; Jackson, HJ; McGorry, PD