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References (140)
-
D. Edwall, P. Prisell, A. Levinovitz, E. Jennische, G. Norstedt (1992)
Expression of insulin‐like growth factor I messenger ribonucleic acid in regenerating bone after fracture: Influence of indomethacinJournal of Bone and Mineral Research, 7
-
A. Valtola, R. Honkanen, H. Kröger, M. Tuppurainen, S. Saarikoski, E. Alhava (2002)
Lifestyle and other factors predict ankle fractures in perimenopausal women: a population-based prospective cohort study.Bone, 30 1
-
S. Varghese, E. Canalis (2000)
Alendronate Stimulates Collagenase 3 Expression in Osteoblasts by Posttranscriptional MechanismsJournal of Bone and Mineral Research, 15
-
R. Bockman, P. Guidon, L. Pan, R. Salvatori, Alan Kawaguchi (1993)
Gallium nitrate increases type I collagen and fibronectin mRNA and collagen protein levels in bone and fibroblast cellsJournal of Cellular Biochemistry, 52
-
G. Gong, Mark Johnson, M. Barger-Lux, Robert Heaney (1999)
Association of Bone Dimensions with a Parathyroid Hormone Gene Polymorphism in WomenOsteoporosis International, 9
-
C. Khanna, J. Khan, Phoung Nguyen, J. Prehn, J. Caylor, C. Yeung, J. Trepel, P. Meltzer, L. Helman (2001)
Metastasis-associated differences in gene expression in a murine model of osteosarcoma.Cancer research, 61 9
-
S. Hui, C. Slemenda, C. Johnston (1989)
Baseline measurement of bone mass predicts fracture in white women.Annals of internal medicine, 111 5
-
O. Hill (1968)
A Twin StudyBritish Journal of Psychiatry, 114
-
I. Iwamoto, S. Kosha, T. Fujino, Y. Nagata (2002)
Effects of Vitamin K2 on Bone of Ovariectomized Rats and on a Rat Osteoblastic Cell LineGynecologic and Obstetric Investigation, 53
-
N. Risch, K. Merikangas (1996)
The Future of Genetic Studies of Complex Human DiseasesScience, 273
-
D. Black, S. Cummings, L. Melton (1992)
Appendicular bone mineral and a woman's lifetime risk of hip fractureJournal of Bone and Mineral Research, 7
-
H. Zhang, H. Lu, S. Enosawa, S. Takahara, K. Sakamoto, T. Nakajima, H. Saito, S. Suzuki (2002)
Microarray analysis of gene expression in peripheral blood mononuclear cells derived from long-surviving renal recipients.Transplantation proceedings, 34 5
-
LG Raisz (1988)
Local and systemic factors in the pathogenesis of osteoporosisN Engl J Med, 318
-
Fina Liu, J. Aubin, L. Malaval (2002)
Expression of leukemia inhibitory factor (LIF)/interleukin-6 family cytokines and receptors during in vitro osteogenesis: differential regulation by dexamethasone and LIF.Bone, 31 1
-
C. Slemenda, MD Christian, PhD Reed, MS Reister, PhD Williams, Jr. Johnston, Drph (1992)
Long-Term Bone Loss in Men: Effects of Genetic and Environmental FactorsAnnals of Internal Medicine, 117
-
L Audi, M Garcia-Ramirez, A Carrascosa (1999)
Genetic determinants of bone massHorm Res, 51
-
Yasuhiro Takeuchi, M. Suzawa, Seiji Fukumoto, T. Fujita (2000)
Vitamin K(2) inhibits adipogenesis, osteoclastogenesis, and ODF/RANK ligand expression in murine bone marrow cell cultures.Bone, 27 6
-
H. Deng, Wei-Min Chen, T. Conway, Yan Zhou, K. Davies, M. Stegman, H. Deng, R. Recker (2000)
Determination of bone mineral density of the hip and spine in human pedigrees by genetic and life‐style factorsGenetic Epidemiology, 19
-
M Kleerekoper, AR Villanueva, J Stanciu (1985)
The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fracturesCalcif Tissue Int, 37
-
L. Raisz (1988)
Local and systemic factors in the pathogenesis of osteoporosis.World review of nutrition and dietetics, 72
-
D. Lacey, J. Erdmann, H. Tan, J. Ohara (1993)
Murine osteoblast interleukin 4 receptor expression: Upregulation by 1,25 dihydroxyvitamin D3Journal of Cellular Biochemistry, 53
-
M. Nasu, T. Sugimoto, H. Kaji, Kazuo Chihara (2000)
Estrogen modulates osteoblast proliferation and function regulated by parathyroid hormone in osteoblastic SaOS-2 cells: role of insulin-like growth factor (IGF)-I and IGF-binding protein-5.The Journal of endocrinology, 167 2
-
K. Faulkner, S. Cummings, D. Black, L. Palermo, C. Glüer, H. Genant (1993)
Simple measurement of femoral geometry predicts hip fracture: The study of osteoporotic fracturesJournal of Bone and Mineral Research, 8
-
N. Ho, L. Jia, Catherine Driscoll, E. Gutter, C. Francomano, M. Drezner (2000)
A Skeletal Gene DatabaseJournal of Bone and Mineral Research, 15
-
T. Grewal, P. Genever, Alex Brabbs, M. Birch, T. Skerry (2000)
Best5: a novel interferon‐inducible gene expressed during bone formationThe FASEB Journal, 14
-
D. Kuprash, V. Boitchenko, F. Yarovinsky, N. Rice, A. Nordheim, A. Rühlmann, S. Nedospasov (2002)
Cyclosporin A blocks the expression of lymphotoxin α, but not lymphotoxin β, in human peripheral blood mononuclear cellsBlood, 100
-
M. Bakay, Yi-Wen Chen, R. Borup, P. Zhao, K. Nagaraju, E. Hoffman (2002)
Sources of variability and effect of experimental approach on expression profiling data interpretationBMC Bioinformatics, 3
-
L. Hofbauer, C. Dunstan, T. Spelsberg, B. Riggs, S. Khosla (1998)
Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines.Biochemical and biophysical research communications, 250 3
-
D. Stokes, Gang Liu, I. Coimbra, S. Piera-velázquez, R. Crowl, S. Jimenez (2002)
Assessment of the gene expression profile of differentiated and dedifferentiated human fetal chondrocytes by microarray analysis.Arthritis and rheumatism, 46 2
-
K. Han, Ji Choi, I. Moon, Hyun Yoon, In-Kwon Han, H. Min, Young Kim, Young Choi (1999)
Non-association of Estrogen Receptor Genotypes with Bone Mineral Density and Bone Turnover in Korean Pre-, Peri-, and Postmenopausal WomenOsteoporosis International, 9
-
Herzl Ben-Hur, G. Mor, V. Insler, I. Blickstein, Y. Amir-Zaltsman, A. Sharp, A. Globerson, F. Kohen (1995)
Menopause Is Associated With a Significant Increase in Blood Monocyte Number and a Relative Decrease in the Expression of Estrogen Receptors in Human Peripheral MonocytesAmerican Journal of Reproductive Immunology, 34
-
S. Ralston (1994)
Analysis of gene expression in human bone biopsies by polymerase chain reaction: Evidence for enhanced cytokine expression in postmenopausal osteoporosisJournal of Bone and Mineral Research, 9
-
MC Nevitt, SR Cummings (1993)
Type of fall and risk of hip and wrist fractures: the study of osteoporotic fractures. The Study of Osteoporotic Fractures Research GroupJ Am Geriatr Soc, 41
-
G. Lisignoli, A. Piacentini, S. Toneguzzi, F. Grassi, B. Cocchini, A. Ferruzzi, Gualtiero Gualtieri, Annalisa Facchini (2000)
Osteoblasts and stromal cells isolated from femora in rheumatoid arthritis (RA) and osteoarthritis (OA) patients express IL‐11, leukaemia inhibitory factor and oncostatin MClinical & Experimental Immunology, 119
-
J. Connor, Sanjay Kumar, G. Sathe, J. Mooney, S. O'Brien, P. Mui, P. Murdock, M. Gowen, M. Lark (2001)
Clusterin expression in adult human normal and osteoarthritic articular cartilage.Osteoarthritis and cartilage, 9 8
-
W. Gu, Xinmin Li, William Lau, B. Edderkaoui, L. Donahae, C. Rosen, W. Beamer, K. Shultz, A. Srivastava, S. Mohan, D. Baylink (2002)
Gene expression between a congenic strain that contains a quantitative trait locus of high bone density from CAST/EiJ and its wild-type strain C57BL/6JFunctional & Integrative Genomics, 1
-
L. Hofbauer, S. Khosla, C. Dunstan, D. Lacey, W. Boyle, B. Riggs (2000)
The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone ResorptionJournal of Bone and Mineral Research, 15
-
M. Nevitt, S. Cummings (1993)
TYPE OF FALL AND RISK OF HIP AND WRIST FRACTURES: THE STUDY OF OSTEOPOROTIC FRACTURESJournal of the American Geriatrics Society, 42
-
T. Hosoi, M. Miyao, S. Inoue, S. Hoshino, M. Shiraki, H. Orimo, Y. Ouchi (1999)
Association Study of Parathyroid Hormone Gene Polymorphism and Bone Mineral Density in Japanese Postmenopausal WomenCalcified Tissue International, 64
-
F. Gori, L. Hofbauer, Colin Dunstan, T. Spelsberg, S. Khosla, B. Riggs (2000)
The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated.Endocrinology, 141 12
-
A. Raouf, A. Seth (2002)
Discovery of osteoblast-associated genes using cDNA microarrays.Bone, 30 3
-
S. Chiba, M. Un-No, R. Neer, K. Okada, G. Serge, Kaechoong Lee (2002)
Parathyroid hormone induces interleukin-6 gene expression in bone stromal cells of young rats.The Journal of veterinary medical science, 64 7
-
George Beck, Brad Zerler, Elizabeth Moran (2001)
Gene array analysis of osteoblast differentiation.Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 12 2
-
B. Crombrugghe, V. Lefebvre, R. Behringer, Weimin Bi, S. Murakami, Wendong Huang (2000)
Transcriptional mechanisms of chondrocyte differentiation.Matrix biology : journal of the International Society for Matrix Biology, 19 5
-
N. Ramamurthy, S. Bain, C. Liang, J. Barnes, A. Llavaneras, Y. Liu, D. Puerner, M. Strachan, L. Golub (2001)
A combination of subtherapeutic doses of chemically modified doxycycline (CMT-8) and a bisphosphonate (clodronate) inhibits bone loss in the ovariectomized rat: a dynamic histomorphometric and gene expression study.Current medicinal chemistry, 8 3
-
B. Lecka-Czernik, I. Gubrij, E. Moerman, O. Kajkenova, D. Lipschitz, S. Manolagas, R. Jilka (1999)
Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARγ2Journal of Cellular Biochemistry, 74
-
D. Burr, R. Martin, M. Schaffler, E. Radin (1985)
Bone remodeling in response to in vivo fatigue microdamage.Journal of biomechanics, 18 3
-
S. Kobayashi, S. Inoue, T. Hosoi, Y. Ouchi, M. Shiraki, H. Orimo (1996)
Association of bone mineral density with polymorphism of the estrogen receptor geneJournal of Bone and Mineral Research, 11
-
H. Deng, Xu-Tao Deng, T. Conway, Fu-Hua Xu, R. Heaney, R. Recker (2002)
Determination of bone size of hip, spine, and wrist in human pedigrees by genetic and lifestyle factors.Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 5 1
-
(1996)
Vitamin D receptor (VDR) genotype influence on bone mass in transmenopausal women -
S. Srivastava, M. Weitzmann, R. Kimble, M. Rizzo, M. Zahner, J. Milbrandt, F. Ross, R. Pacifici (1998)
Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1.The Journal of clinical investigation, 102 10
-
M. Saika, D. Inoue, S. Kido, Toshio Matsumoto (2001)
17β-Estradiol Stimulates Expression of Osteoprotegerin by a Mouse Stromal Cell Line, ST-2, via Estrogen Receptor-α.Endocrinology, 142 6
-
R. Heller, M. Schena, A. Chai, D. Shalon, Tod Bedilion, J. Gilmore, D. Woolley, Ronald Davis (1997)
Discovery and analysis of inflammatory disease-related genes using cDNA microarrays.Proceedings of the National Academy of Sciences of the United States of America, 94 6
-
(1995)
Linkage analysis in seven families with low bone mineral density -
H. Kaji, T. Sugimoto, M. Kanatani, M. Fukase, M. Kumegawa, K. Chihara (1996)
Prostaglandin E2 stimulates osteoclast‐like cell formation and bone‐resorbing activity via osteoblasts: Role of cAMP‐dependent protein kinaseJournal of Bone and Mineral Research, 11
-
Charles Epstein, R. Butow (2000)
Microarray technology - enhanced versatility, persistent challenge.Current opinion in biotechnology, 11 1
-
D. Chikazu, Xiaodong Li, H. Kawaguchi, Y. Sakuma, O. Voznesensky, D. Adams, Manshan Xu, K. Hoshi, V. Katavić, H. Herschman, L. Raisz, C. Pilbeam (2005)
Bone Morphogenetic Protein 2 Induces Cyclo‐oxygenase 2 in Osteoblasts via a Cbfa1 Binding Site: Role in Effects of Bone Morphogenetic Protein 2 In Vitro and In VivoJournal of Bone and Mineral Research, 20
-
K. Furushima, Kazuki Shimo-onoda, S. Maeda, T. Nobukuni, K. Ikari, H. Koga, S. Komiya, T. Nakajima, S. Harata, I. Inoue (2002)
Large‐Scale Screening for Candidate Genes of Ossification of the Posterior Longitudinal Ligament of the SpineJournal of Bone and Mineral Research, 17
-
M. Iwase, Kang-Jung Kim, Yoshiro Kobayashi, M. Itoh, T. Itoh (2002)
A novel bisphosphonate inhibits inflammatory bone resorption in a rat osteolysis model with continuous infusion of polyethylene particlesJournal of Orthopaedic Research, 20
-
N. Ray, Julien Chan, M. Thamer, L. Melton (1997)
Medical Expenditures for the Treatment of Osteoporotic Fractures in the United States in 1995: Report from the National Osteoporosis FoundationJournal of Bone and Mineral Research, 12
-
P. Salomon, A. Pizzimenti, A. Panja, A. Reisman, L. Mayer (1991)
The expression and regulation of class II antigens in normal and inflammatory bowel disease peripheral blood monocytes and intestinal epithelium.Autoimmunity, 9 2
-
S. Ralston (1997)
Genetic markers of bone metabolism and bone disease.Scandinavian journal of clinical and laboratory investigation. Supplementum, 227
-
M. Møller, A. Horsman, B. Harvald, M. Hauge, K. Henningsen, B. Nordin (1978)
Metacarpal morphometry in monozygotic and dizygotic elderly twinsCalcified Tissue Research, 25
-
(1995)
Vitamin D receptor gene polymorphism and peak bone mass -
KD Ward, RC Klesges (2001)
A meta-analysis of the effects of cigarette smoking on bone mineral densityCalcif Tissue Int, 68
-
O. Albagha, F. Mcguigan, D. Reid, S. Ralston (2001)
Estrogen Receptor α Gene Polymorphisms and Bone Mineral Density: Haplotype Analysis in Women from the United KingdomJournal of Bone and Mineral Research, 16
-
A. Stewart (1996)
PTHrP(1-36) as a skeletal anabolic agent for the treatment of osteoporosis.Bone, 19 4
-
J. Bilezikian, L. Raisz, G. Rodan (1996)
Principles of Bone Biology -
D. Kuprash, V. Boitchenko, F. Yarovinsky, N. Rice, A. Nordheim, A. Rühlmann, S. Nedospasov (2002)
Cyclosporin A blocks the expression of lymphotoxin alpha, but not lymphotoxin beta, in human peripheral blood mononuclear cells.Blood, 100 5
-
T. Maeda, A. Matsunuma, T. Kawane, N. Horiuchi (2001)
Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells.Biochemical and biophysical research communications, 280 3
-
CC Gluer, SR Cummings, A Pressman (1994)
Prediction of hip fractures from pelvic radiographs: the study of osteoporotic fractures. The Study of Osteoporotic Fractures Research GroupJ Bone Miner Res, 9
-
J. Theilhaber, T. Connolly, S. Roman-Roman, S. Bushnell, Amanda Jackson, K. Call, Teresa Garcia, R. Baron (2002)
Finding genes in the C2C12 osteogenic pathway by k-nearest-neighbor classification of expression data.Genome research, 12 1
-
L. Melton, S. Kan, M. Frye, H. Wahner, W. O'Fallon, B. Riggs (1989)
Epidemiology of vertebral fractures in women.American journal of epidemiology, 129 5
-
A. Mizuno, A. Murakami, N. Nakagawa, H. Yasuda, E. Tsuda, T. Morinaga, K. Higashio (1998)
Structure of the mouse osteoclastogenesis inhibitory factor (OCIF) gene and its expression in embryogenesis.Gene, 215 2
-
D. Feskanich, P. Weber, W. Willett, H. Rockett, S. Booth, G. Colditz (1999)
Vitamin K intake and hip fractures in women: a prospective study.The American journal of clinical nutrition, 69 1
-
K. Dahlquist, N. Salomonis, K. Vranizan, Steven Lawlor, B. Conklin (2002)
GenMAPP, a new tool for viewing and analyzing microarray data on biological pathwaysNature Genetics, 31
-
M. Schena, R. Heller, Thomas Theriault, Ken Konrad, E. Lachenmeier, Ronald Davis (1998)
Microarrays: biotechnology's discovery platform for functional genomics.Trends in biotechnology, 16 7
-
W. Huang, B. Carlsen, G. Rudkin, N. Shah, C. Chung, K. Ishida, D. Yamaguchi, T. Miller (2001)
Effect of serial passage on gene expression in MC3T3-E1 preosteoblastic cells: a microarray study.Biochemical and biophysical research communications, 281 5
-
Daniel Koller, Michael Econs, P. Morin, J. Christian, S. Hui, Pauline Parry, M. Curran, Lawrence Rodriguez, P. Conneally, G. Joslyn, M. Peacock, C. Johnston, T. Foroud (2000)
Genome screen for QTLs contributing to normal variation in bone mineral density and osteoporosis.The Journal of clinical endocrinology and metabolism, 85 9
-
T. McCarthy, M. Centrella, E. Canalis (1990)
Cortisol inhibits the synthesis of insulin-like growth factor-I in skeletal cells.Endocrinology, 126 3
-
SR Cummings, JL Kelsey, MC Nevitt (1985)
Epidemiology of osteoporosis and osteoporotic fracturesEpidemiol Rev, 7
-
Momiao Xiong, Julia Krushkal, Eric Boerwinkle (1998)
TDT statistics for mapping quantitative trait lociAnnals of Human Genetics, 62
-
R. Power, U. Iwaniec, T. Wronski (2002)
Changes in gene expression associated with the bone anabolic effects of basic fibroblast growth factor in aged ovariectomized rats.Bone, 31 1
-
R. Locklin, B. Riggs, K. Hicok, H. Horton, M. Byrne, S. Khosla (2001)
Assessment of Gene Regulation by Bone Morphogenetic Protein 2 in Human Marrow Stromal Cells Using Gene Array TechnologyJournal of Bone and Mineral Research, 16
-
S. Wakabayashi, T. Tsutsumimoto, S. Kawasaki, T. Kinoshita, H. Horiuchi, K. Takaoka (2002)
Involvement of Phosphodiesterase Isozymes in Osteoblastic DifferentiationJournal of Bone and Mineral Research, 17
-
L. Hofbauer, C. Shui, B. Riggs, C. Dunstan, T. Spelsberg, T. O'Brien, S. Khosla (2001)
Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells.Biochemical and biophysical research communications, 280 1
-
L. Hofbauer, F. Gori, B. Riggs, D. Lacey, C. Dunstan, T. Spelsberg, S. Khosla (1999)
Stimulation of Osteoprotegerin Ligand and Inhibition of Osteoprotegerin Production by Glucocorticoids in Human Osteoblastic Lineage Cells: Potential Paracrine Mechanisms of Glucocorticoid-Induced Osteoporosis1.Endocrinology, 140 10
-
M. Zayzafoon, C. Stell, Regina Irwin, L. McCabe (2000)
Extracellular glucose influences osteoblast differentiation and c–jun expressionJournal of Cellular Biochemistry, 79
-
S. Cummings, S. Rubin, D. Black (1990)
The future of hip fractures in the United States. Numbers, costs, and potential effects of postmenopausal estrogen.Clinical orthopaedics and related research, 252
-
C. Glüer, S. Cummings, A. Pressman, Jiao Li, Kathrin Glüer, K. Faulkner, S. Grampp, H. Genant (1994)
Prediction of hip fractures from pelvic radiographs: The study of osteoporotic fracturesJournal of Bone and Mineral Research, 9
-
P. Szulc, P. Garnero, B. Claustrat, F. Marchand, F. Duboeuf, P. Delmas (2002)
Increased bone resorption in moderate smokers with low body weight: the Minos study.The Journal of clinical endocrinology and metabolism, 87 2
-
DB Allison (1997)
Transmission-disequilibrium tests for quantitative traitsAm J Hum Genet, 60
-
N. Bucay, I. Sarosi, C. Dunstan, S. Morony, J. Tarpley, C. Capparelli, S. Scully, H. Tan, Wei-wei Xu, D. Lacey, W. Boyle, W. Simonet (1998)
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.Genes & development, 12 9
-
Hideki Mizunuma, T. Hosoi, H. Okano, M. Soda, T. Tokizawa, I. Kagami, S. Miyamoto, Yosito Ibuki, S. Inoue, M. Shiraki, Yasuyoshi Ouchi (1997)
Estrogen receptor gene polymorphism and bone mineral density at the lumbar spine of pre- and postmenopausal women.Bone, 21 5
-
M. Fini, P. Torricelli, G. Giavaresi, A. Carpi, A. Nicolini, R. Giardino (2001)
Effect of L-lysine and L-arginine on primary osteoblast cultures from normal and osteopenic rats.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 55 4
-
W. Simonet, D. Lacey, C. Dunstan, M. Kelley, Ming-Shi Chang, R. Lüthy, Hung Nguyen, S. Wooden, L. Bennett, T. Boone, G. Shimamoto, M. DeRose, R. Elliott, A. Colombero, H. Tan, Geraldine Trail, J. Sullivan, E. Davy, N. Bucay, L. Renshaw-Gegg, T. Hughes, D. Hill, W. Pattison, P. Campbell, S. Sander, G. Van, J. Tarpley, P. Derby, R. Lee, W. Boyle (1997)
Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone DensityCell, 89
-
T. Hughes, M. Marton, Allan Jones, C. Roberts, R. Stoughton, C. Armour, Holly Bennett, E. Coffey, H. Dai, Yudong He, M. Kidd, Amy King, Michael Meyer, D. Slade, P. Lum, S. Stepaniants, D. Shoemaker, D. Gachotte, K. Chakraburtty, J. Simon, M. Bard, S. Friend (2000)
Functional Discovery via a Compendium of Expression ProfilesCell, 102
-
C. Fargeas, C. Wu, H. Luo, M. Sarfati, G. Delespesse, J. Wu (1990)
1,25(OH)2 vitamin D3 inhibits the CD23 gene expression by human peripheral blood monocytes.Journal of immunology, 145 12
-
S. Hui, C. Slemenda, C. Johnston (1988)
Age and bone mass as predictors of fracture in a prospective study.The Journal of clinical investigation, 81 6
-
D. Stanislaus, V. Devanarayan, J. Hock (2000)
In vivo comparison of activated protein-1 gene activation in response to human parathyroid hormone (hPTH)(1-34) and hPTH(1-84) in the distal femur metaphyses of young mice.Bone, 27 6
-
M. Weinreb, M. Machwate, N. Shir, M. Abramovitz, G. Rodan, S. Harada (2001)
Expression of the prostaglandin E2 (PGE2) receptor subtype EP4 and its regulation by PGE2 in osteoblastic cell lines and adult rat bone tissue1Bone, 28
-
A. Mizuno, N. Amizuka, K. Irie, A. Murakami, N. Fujise, Takeshi Kanno, Yasushi Sato, N. Nakagawa, H. Yasuda, S. Mochizuki, T. Gomibuchi, K. Yano, N. Shima, N. Washida, E. Tsuda, T. Morinaga, K. Higashio, H. Ozawa (1998)
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin.Biochemical and biophysical research communications, 247 3
-
S. Shi, P. Robey, S. Gronthos (2001)
Comparison of human dental pulp and bone marrow stromal stem cells by cDNA microarray analysis.Bone, 29 6
-
B. Ongphiphadhanakul, R. Rajatanavin, S. Chanprasertyothin, N. Piaseu, L. Chailurkit, R. Sirisriro, S. Komindr (1998)
Estrogen receptor gene polymorphism is associated with bone mineral density in premenopausal women but not in postmenopausal womenJournal of Endocrinological Investigation, 21
-
L. Spotila, A. Colige, L. Sereda, C. Constantinou‐Deltas, M. Whyte, L. Riggs, J. Shaker, T. Spector, E. Hume, N. Olsen, M. Attie, A. Tenenhouse, E. Shane, W. Briney, D. Prockop (1994)
Mutation analysis of coding sequences for type I procollagen in individuals with low bone densityJournal of Bone and Mineral Research, 9
-
Y. Akiyama, K. Hara, T. Tajima, S. Murota, I. Morita (1994)
Effect of vitamin K2 (menatetrenone) on osteoclast-like cell formation in mouse bone marrow cultures.European journal of pharmacology, 263 1-2
-
J. Beresford, Jh Bennett, C. Devlin, P. Leboy, M. Owen (1992)
Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell cultures.Journal of cell science, 102 ( Pt 2)
-
M. Møller, A. Horsman, B. Harvald, M. Hauge, K. Henningsen, B. Nordin (1978)
Metacarpal morphometry in monozygotic dizygotic elderly twins.Calcified tissue research, 25 2
-
J. Tomlinson, I. Bujalska, P. Stewart, M. Cooper (2000)
The Role of 11 β-Hydroxysteroid Dehydrogenase in Central Obesity and OsteoporosisEndocrine Research, 26
-
P. Ducy, Rui Zhang, V. Geoffroy, A. Ridall, G. Karsenty (1997)
Osf2/Cbfa1: A Transcriptional Activator of Osteoblast DifferentiationCell, 89
-
H. Deng, Jian Li, Jin-long Li, M. Johnson, G. Gong, R. Recker (1999)
Association of VDR and Estrogen Receptor Genotypes with Bone Mass in Postmenopausal Caucasian Women: Different Conclusions with Different Analyses and the ImplicationsOsteoporosis International, 9
-
C. Rosen, E. Kurland, D. Vereault, R. Adler, P. Rackoff, W. Craig, S. Witte, J. Rogers, J. Bilezikian (1998)
Association between serum insulin growth factor-I (IGF-I) and a simple sequence repeat in IGF-I gene: implications for genetic studies of bone mineral density.The Journal of clinical endocrinology and metabolism, 83 7
-
M. Vincenti, C. Brinckerhoff (2001)
Early response genes induced in chondrocytes stimulated with the inflammatory cytokine interleukin-1betaArthritis Research, 3
-
M. Doi, A. Nagano, Yusuke Nakamura (2002)
Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro.Biochemical and biophysical research communications, 290 1
-
L. Hofbauer, S. Khosla, C. Dunstan, D. Lacey, T. Spelsberg, B. Riggs (1999)
Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells.Endocrinology, 140 9
-
B. Burguera, L. Hofbauer, T. Thomas, F. Gori, G. Evans, S. Khosla, B. Riggs, R. Turner (2001)
Leptin reduces ovariectomy-induced bone loss in rats.Endocrinology, 142 8
-
Walsh, M. Birch, W. Fraser, Andrew Ginty, J. Gallagher (2000)
Cytokine expression by cultured osteoblasts from patients with osteoporotic fracturesInternational Journal of Experimental Pathology, 81
-
J. Davis, R. Novotny, R. Wasnich, P. Ross (1999)
Ethnic, Anthropometric, and Lifestyle Associations with Regional Variations in Peak Bone MassCalcified Tissue International, 65
-
L. Spotila, J. Caminis, M. Devoto, K. Shimoya, L. Sereda, J. Ott, M. Whyte, A. Tenenhouse, D. Prockop (1996)
Osteopenia in 37 Members of Seven Families: Analysis Based on a Model of Dominant InheritanceMolecular Medicine, 2
-
J. Gimble, C. Robinson, S. Clarke, M. Hill (1998)
Nuclear hormone receptors and adipogenesis.Critical reviews in eukaryotic gene expression, 8 2
-
N. Hal, O. Vorst, A. Houwelingen, E. Kok, A. Peijnenburg, A. Aharoni, A. Tunen, J. Keijer (2000)
The application of DNA microarrays in gene expression analysis.Journal of biotechnology, 78 3
-
L. Hofbauer, D. Lacey, C. Dunstan, T. Spelsberg, B. Riggs, S. Khosla (1999)
Interleukin-1β and tumor necrosis factor-α, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cellsBone, 25
-
L. Spotila, C. Constantinou, L. Sereda, A. Ganguly, B. RIGGSt, J. Darwin, PROCKOPf (1991)
Mutation in a gene for type I procollagen (COL1A2) in a woman with postmenopausal osteoporosis: evidence for phenotypic and genotypic overlap with mild osteogenesis imperfecta.Proceedings of the National Academy of Sciences of the United States of America, 88
-
K. Ohnaka, Seiko Shimoda, H. Nawata, H. Shimokawa, K. Kaibuchi, Y. Iwamoto, R. Takayanagi (2001)
Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblasts.Biochemical and biophysical research communications, 287 2
-
K. Hara, Y. Akiyama, T. Nakamura, Sei-itsu Murota, I. Morita (1995)
The inhibitory effect of vitamin K2 (menatetrenone) on bone resorption may be related to its side chain.Bone, 16 2
-
Y. Yoshida, Sakae Tanaka, H. Umemori, O. Minowa, M. Usui, N. Ikematsu, Eri Hosoda, T. Imamura, J. Kuno, T. Yamashita, K. Miyazono, M. Noda, T. Noda, Tadashi Yamamoto (2000)
Negative Regulation of BMP/Smad Signaling by Tob in OsteoblastsCell, 103
-
H. Deng, M. Stegman, K. Davies, T. Conway, R. Recker (1999)
Genetic determination of variation and covariation of peak bone mass at the hip and spine.Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 2 3
-
A. Bennett, H. Wahner, B. Riggs, R. Hintz (1984)
Insulin-like growth factors I and II: aging and bone density in women.The Journal of clinical endocrinology and metabolism, 59 4
-
M. Lunt, P. Masaryk, C. Scheidt-Nave, J. Nijs, G. Poór, H. Pols, J. Falch, G. Hammermeister, D. Reid, L. Benevolenskaya, K. Weber, J. Cannata, T. O’Neill, D. Felsenberg, A. Silman, J. Reeve (2001)
The Effects of Lifestyle, Dietary Dairy Intake and Diabetes on Bone Density and Vertebral Deformity Prevalence: The EVOS StudyOsteoporosis International, 12
-
(2002)
Cells of bone : osteoclast generation -
J. Dequeker, J. Nijs, A. Verstraeten, P. Geusens, G. Gevers (1987)
Genetic determinants of bone mineral content at the spine and radius: a twin study.Bone, 8 4
-
N. Pocock, J. Eisman, J. Hopper, M. Yeates, P. Sambrook, S. Eberl (1987)
Genetic determinants of bone mass in adults. A twin study.The Journal of clinical investigation, 80 3
-
T. Bellido, R. Jilka, B. Boyce, G. Girasole, H. Broxmeyer, S. Dalrymple, R. Murray, S. Manolagas (1995)
Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptor.The Journal of clinical investigation, 95 6
-
Jung-Ren Chen, Q. Zhong, Jian Wang, R. Cameron, J. Borke, C. Isales, R. Bollag (2001)
Microarray analysis of Tbx2-directed gene expression: a possible role in osteogenesisMolecular and Cellular Endocrinology, 177
-
M. Enomoto-Iwamoto, H. Enomoto, T. Komori, M. Iwamoto (2001)
Participation of Cbfa1 in regulation of chondrocyte maturation.Osteoarthritis and cartilage, 9 Suppl A
-
T. Komori, H. Yagi, S. Nomura, Akira Yamaguchi, Koichi Sasaki, K. Deguchi, Y. Shimizu, R. Bronson, Y-H Gao, Masahiko Inada, Makoto Sato, R. Okamoto, Yukihiko Kitamura, S. Yoshiki, T. Kishimoto (1997)
Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of OsteoblastsCell, 89
-
P. Baldock, J. Eisman (2004)
Genetic determinants of bone massCurrent Opinion in Rheumatology, 16
-
D. Stanislaus, X. Yang, J.D Liang, J. Wolfe, R. Cain, J. Onyia, N. Falla, P. Marder, J. Bidwell, S. Queener, J. Hock (2000)
In vivo regulation of apoptosis in metaphyseal trabecular bone of young rats by synthetic human parathyroid hormone (1-34) fragment.Bone, 27 2
-
Xiaofeng Zhu, R. Elston (2001)
Transmission/disequilibrium tests for quantitative traitsGenetic Epidemiology, 20
-
(1995)
Vitamin D receptor (VDR) gene polymorphism: Relationship to adult bone expansion, bone loss and body size in longitudinal data
- Publisher
- Springer Journals
- Copyright
- Copyright © 2003 by International Osteoporosis Foundation and National Osteoporosis Foundation
- Subject
- Medicine & Public Health; Orthopedics; Endocrinology; Rheumatology
- ISSN
- 0937-941X
- eISSN
- 1433-2965
- DOI
- 10.1007/s00198-002-1373-0
- pmid
- 12730742
- Publisher site
- See Article on Publisher Site
Abstract
Osteoporosis is one of the most common bone-related disorders in the elderly. It is a complex disease, and largely determined genetically. Traditional gene expression studies have shown that osteoporosis has complex regulating mechanisms which are controlled by multiple inherent factors, such as hormones, cytokines, various receptors, etc. The complex nature of osteoporosis, and the large number of genes involved in its onset and development, suggest the use of the state of the art microarray technique as a powerful tool to unravel mechanisms underlying etiology of osteoporosis.
Journal
Osteoporosis International – Springer Journals
Published: Apr 29, 2003