Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Gastrointestinal Stromal Tumour in a Patient with Multiple Cutaneous and Uterine Leiomyomatosis- Implications and Anaesthetic Management

Gastrointestinal Stromal Tumour in a Patient with Multiple Cutaneous and Uterine Leiomyomatosis-... Abstract Multiple cutaneous leiomyomatosis have been associated with uterine leiomyomatosis and known as Reed’s syndrome or Multiple Cutaneous and Uterine Leiomyomatosis (MCUL). Gastrointestinal Stromal Tumours (GIST) have been reported to be associated with this syndrome only once previously in literature to the best of our knowledge. Here we report a rare case of GIST and multiple uterine leiomyomatosis in a middle aged patient with longstanding cutaneous leiomyomatosis who underwent GIST excision and hysterectomy. A 35 year old female patient with multiple cutaneous leiomyomatosis for the past 20 years was diagnosed to have gastrointestinal stromal tumour and multiple uterine leiomyomatosis for which she underwent laparotomy for GIST excision and hysterectomy. In the report we have elaborated the clinical and pathological observations as well as the anaesthetic management. This case report further substantiates the association of GIST with multiple cutaneous and uterine leiomyomatosis and also reminds us that cutaneous lesions can be clues to the diagnosis of underlying malignancy. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Indian Journal of Surgical Oncology Springer Journals

Gastrointestinal Stromal Tumour in a Patient with Multiple Cutaneous and Uterine Leiomyomatosis- Implications and Anaesthetic Management

Download PDF
4 pages

Loading next page...
 
/lp/springer-journals/gastrointestinal-stromal-tumour-in-a-patient-with-multiple-cutaneous-eXZMF49guj
Publisher
Springer Journals
Copyright
2014 Indian Association of Surgical Oncology
ISSN
0975-7651
eISSN
0976-6952
DOI
10.1007/s13193-014-0366-8
Publisher site
See Article on Publisher Site

Abstract

Abstract Multiple cutaneous leiomyomatosis have been associated with uterine leiomyomatosis and known as Reed’s syndrome or Multiple Cutaneous and Uterine Leiomyomatosis (MCUL). Gastrointestinal Stromal Tumours (GIST) have been reported to be associated with this syndrome only once previously in literature to the best of our knowledge. Here we report a rare case of GIST and multiple uterine leiomyomatosis in a middle aged patient with longstanding cutaneous leiomyomatosis who underwent GIST excision and hysterectomy. A 35 year old female patient with multiple cutaneous leiomyomatosis for the past 20 years was diagnosed to have gastrointestinal stromal tumour and multiple uterine leiomyomatosis for which she underwent laparotomy for GIST excision and hysterectomy. In the report we have elaborated the clinical and pathological observations as well as the anaesthetic management. This case report further substantiates the association of GIST with multiple cutaneous and uterine leiomyomatosis and also reminds us that cutaneous lesions can be clues to the diagnosis of underlying malignancy.

Journal

Indian Journal of Surgical Oncology – Springer Journals

Published: Jun 1, 2015

Keywords: surgical oncology; oncology; surgery

References

  • Hereditary multiple leiomyoma of the skin
    HW Kloepfer, J Krafchuk, V Derbes
  • Multiple hereditary cutaneous leiomyoma. Study of a systemic case in a male subject related to a family with cutaneous leiomyomatosis and uterine fibromyomatosis
    G Mezzadra
  • Cutaneous leiomyomata with uterine leiomyomata
    WB Reed, R Walker, R Horowitz
  • Familial leiomyomatosiscutis affecting nine family members in two successive generations including four cases of Reed’s syndrome
    RK Mandal, S Koley, S Banerjee
  • Multiple cutaneous and uterine leiomyomas associated with gastric GIST
    M Lamba, S Verma, R Prokopetz
  • Reed’s syndrome: a case of multiple cutaneous and uterine leiomyomas
    JJ Emer, S Solomon, SE Mercer
  • Hereditary cutaneous leiomyomatosis
    SA Braun, S Hanneken, J Reifenberger
  • Cutaneous clues to renal cell carcinoma: hereditary leiomyomatosis and renal cell carcinoma
    MA Michelon, CJ Layton, CJ Jessup
  • Multiple cutaneous and uterine leiomyomatosis in a 36-year-old female, and discussion of hereditary leiomyomatosis and renal cell carcinoma
    ND Henley, VA Tokarz
  • Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
    IP Tomlinson, NA Alam, AJ Rowan
  • Gastric leiomyoma and hyperplastic polyposis coli in a patient with multiple cutaneous and uterine leiomyomatosis
    D Serra, P Amaro, M Gonçalo
  • Hypertensive crisis during wide excision of gastrointestinal stromal cell tumor (GIST): undiagnosed paraganglioma - a case report
    HK Shinn, JK Jung, JK Park
  • Pathophysiology, diagnosis, and treatment ofgastrointestinal stromal tumors
    Y Shinomura, K Kinoshita, S Tsutsui, S Hirota
  • Gastrointestinal stromal tumors and shock
    KI MajdoubHassani, FZ Zahid, A Ousadden
  • Gastrointestinal stromal tumors (GIST) related emergencies
    MA Sorour, MI Kassem, A-H Ghazal
  • Evidence-guided surgical management of GIST: beyond a simple case of benign and malignant
    C Raut, R Dematteo
  • Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis
    M Miettinen, J Lasota