Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Flavonoids of Geranium pusillum

Flavonoids of Geranium pusillum Chemistry of Natural Compounds, Vol. 38, No. 2, 2002 K. B. Kobakhidze and M. D. Alaniya UDC 547.972 In continuation of a study of the flavonoids of the epigeal part of Geranium pusillum L. (Geraniaceae) [1], air-dried raw material that was collected during flowering was exhaustively extracted with ethanol (70%). The alcohol extract was evaporated in vacuum. The moist solid was treated with CHCl to remove lipophilic substances. Flavonoids were extracted from the purified moist solid by ethylacetate (average 2% yield). The ethylacetate fraction was chromatographed over a polyamide column (eluent ethanol—water in various proportions). Repeated rechromatography of the separate fractions gave flavonoid-like 1-6. Bryant cyanidin reaction [2] established that two of these were aglycones whereas the others were glycosides. The isolated flavonoids were identified using UV and IR spectra and chemical transformations compared with authentic samples. Quercetin (1) (3,5,7,3′,4′-pentahydroxyflavone), yellow crystals, C H O , mp 310-312°C, R 0.36 (BAW, 4:1:2), 0.03 15 10 7 (15% CH COOH), UV spectrum (MeOH, λ , nm): 255, 364 sh, 370. The IR spectrum contains absorption bands for hydroxyl 3 max -1 -1 -1 (3385-3300 cm ), γ-pyrone carbonyl (1660 cm ), and aromatic C C (1565, 1516 cm ). Acetylation http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chemistry of Natural Compounds Springer Journals

Flavonoids of Geranium pusillum

Kobakhidze, K.; Alaniya, M.
Chemistry of Natural Compounds , Volume 38 (2) – Oct 10, 2004
Download PDF
2 pages

Loading next page...
 
/lp/springer-journals/flavonoids-of-geranium-pusillum-NMtUAxkR3M

References (4)

Publisher
Springer Journals
Copyright
Copyright © 2002 by Plenum Publishing Corporation
Subject
Pharmacy; Organic Chemistry; Pharmacy
ISSN
0009-3130
eISSN
1573-8388
DOI
10.1023/A:1019612703604
Publisher site
See Article on Publisher Site

Abstract

Chemistry of Natural Compounds, Vol. 38, No. 2, 2002 K. B. Kobakhidze and M. D. Alaniya UDC 547.972 In continuation of a study of the flavonoids of the epigeal part of Geranium pusillum L. (Geraniaceae) [1], air-dried raw material that was collected during flowering was exhaustively extracted with ethanol (70%). The alcohol extract was evaporated in vacuum. The moist solid was treated with CHCl to remove lipophilic substances. Flavonoids were extracted from the purified moist solid by ethylacetate (average 2% yield). The ethylacetate fraction was chromatographed over a polyamide column (eluent ethanol—water in various proportions). Repeated rechromatography of the separate fractions gave flavonoid-like 1-6. Bryant cyanidin reaction [2] established that two of these were aglycones whereas the others were glycosides. The isolated flavonoids were identified using UV and IR spectra and chemical transformations compared with authentic samples. Quercetin (1) (3,5,7,3′,4′-pentahydroxyflavone), yellow crystals, C H O , mp 310-312°C, R 0.36 (BAW, 4:1:2), 0.03 15 10 7 (15% CH COOH), UV spectrum (MeOH, λ , nm): 255, 364 sh, 370. The IR spectrum contains absorption bands for hydroxyl 3 max -1 -1 -1 (3385-3300 cm ), γ-pyrone carbonyl (1660 cm ), and aromatic C C (1565, 1516 cm ). Acetylation

Journal

Chemistry of Natural Compounds – Springer Journals

Published: Oct 10, 2004

There are no references for this article.