When experimental P + M populations were exposed to chronic γ-irradiation (0.31 mGy/h), the highest instability level of the singed-weak (sn w ) locus was observed in F3–F10 with a subsequent decrease and stabilization of the mutation rate. The sn w mutation rate was within the range of spontaneous variation in conditions of P-M hybrid dysgenesis and irradiation of males of the Harwich laboratory strain with active P elements at 1.61 mGy/h. The instability of the sn w locus was significantly higher at lower dose rates (0.23 and 0.31 mGy/h), suggesting a nonlinear dose-effect relationship.
Russian Journal of Genetics – Springer Journals
Published: Apr 26, 2012
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