Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Efficient and convenient preparation of γ-nonalactone, with use of a Dean–Stark trap to remove methanol

Efficient and convenient preparation of γ-nonalactone, with use of a Dean–Stark trap to remove... We describe the development of an efficient and convenient process for preparation of γ-nonalactone. The synthesis was accomplished by free-radical addition of methyl acrylate and n-hexanol. A Dean–Stark trap filled with water and n-hexanol was used to remove the methanol generated during the process. Orthogonal experiments were performed to optimize the reaction conditions, and the desired product, γ-nonalactone, was produced in better than 70 % yield. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Efficient and convenient preparation of γ-nonalactone, with use of a Dean–Stark trap to remove methanol

Download PDF
6 pages

Loading next page...
 
/lp/springer-journals/efficient-and-convenient-preparation-of-nonalactone-with-use-of-a-dean-102Jdfqghu

References (12)

Publisher
Springer Journals
Copyright
Copyright © 2013 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
DOI
10.1007/s11164-013-1066-7
Publisher site
See Article on Publisher Site

Abstract

We describe the development of an efficient and convenient process for preparation of γ-nonalactone. The synthesis was accomplished by free-radical addition of methyl acrylate and n-hexanol. A Dean–Stark trap filled with water and n-hexanol was used to remove the methanol generated during the process. Orthogonal experiments were performed to optimize the reaction conditions, and the desired product, γ-nonalactone, was produced in better than 70 % yield.

Journal

Research on Chemical Intermediates – Springer Journals

Published: Feb 5, 2013

There are no references for this article.