Effects of nicotine and a cannabinoid receptor agonist on negative contrast: distinction between anxiety and disappointment?

Effects of nicotine and a cannabinoid receptor agonist on negative contrast: distinction between... The pattern of results allows for the separation between effects on anxiety and SNC. The block of contrast on PSD 1 was independent of changes in anxiety, since both anxiolytic and anxiogenic drug doses were effective. It is suggested that this may provide an animal model of disappointment in which the cannabinoid system plays an important role. An anxiolytic action would seem to be a necessary, but not a sufficient, action to block SNC on PSD 2. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychopharmacology Springer Journals

Effects of nicotine and a cannabinoid receptor agonist on negative contrast: distinction between anxiety and disappointment?

Psychopharmacology, Volume 177 (1) – Dec 1, 2004

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Publisher
Springer Journals
Copyright
Copyright © 2004 by Springer-Verlag
Subject
Medicine
ISSN
0033-3158
eISSN
1432-2072
DOI
10.1007/s00213-004-1932-5
pmid
15205871
Publisher site
See Article on Publisher Site

Abstract

The pattern of results allows for the separation between effects on anxiety and SNC. The block of contrast on PSD 1 was independent of changes in anxiety, since both anxiolytic and anxiogenic drug doses were effective. It is suggested that this may provide an animal model of disappointment in which the cannabinoid system plays an important role. An anxiolytic action would seem to be a necessary, but not a sufficient, action to block SNC on PSD 2.

Journal

PsychopharmacologySpringer Journals

Published: Dec 1, 2004

References

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