213 33 33 4 4 M. Babbini M. Gaiardi M. Bartoletti Institute of Pharmacology University of Bologna Italy Abstract Rats placed in a test chamber, where they had received repetitive shocks the previous day, strongly reduced their motor activity. This was taken as an indication of a conditioned emotional response (CER). Morphine attenuates this quickly learned conditioned suppression in a dose related manner and the effect does not appear to be a consequence of an influence upon performance, a change in the general stimulus situation or a drug-induced amnesia. It is believed that the action of morphine was due to a reduction of anxiety associated with anticipation of noxious stimuli.
Psychopharmacology – Springer Journals
Published: Dec 1, 1973
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