Access the full text.
Sign up today, get DeepDyve free for 14 days.
(1968)
Effect of early nutr i t ion on the development of ra t epididymal fat pads: Cellulari ty and metabolism
B. Bryant (1966)
THE INCORPORATION OF TRITIUM FROM THYMIDINE INTO PROTEINS OF THE MOUSEThe Journal of Cell Biology, 29
O. Lowry, N. Rosebrough, A. Farr, R. Randall (1951)
Protein measurement with the Folin phenol reagent.The Journal of biological chemistry, 193 1
(1971)
tersuchungen iiber die Zellvermehrung im weil 3 en Fettgewebe dcr genetisch adipSsen Maus ( C 57 BL / 6 J ob / ob )
W. Mohr, G. Beneke (1968)
Age dependence of nuclear DNA content of rat adipose tissue cellsExperientia, 24
C. Hollenberg, A. Vost (1968)
Regulation of DNA synthesis in fat cells and stromal elements from rat adipose tissue.The Journal of clinical investigation, 47 11
W. Malaisse, F. Malaisse‐Lagae (1969)
Chronic effects of insulin and glucagon upon islet functionDiabetologia, 5
A. Renold, Alexander Marble, Don Fawcett (1950)
Action of insulin on deposition of glycogen and storage of fat in adipose tissue.Endocrinology, 46 1
J. Folch, M. Lees, G. Stanley (1957)
A simple method for the isolation and purification of total lipides from animal tissues.The Journal of biological chemistry, 226 1
R. Redman, L. Sreebny (1970)
PROLIFERATIVE BEHAVIOR OF DIFFERENTIATING CELLS IN THE DEVELOPING RAT PAROTID GLANDThe Journal of Cell Biology, 46
(1945)
A method for the determination of DNA , 1 % NA and phosphoproteins in animal tissues
Postnatal development of cellularity of adipose tissue in different strains of rats
B. Szepesi, C. Berdanier (1971)
Time course of the starve-refeed response in rats; the possible role of insulin.The Journal of nutrition, 101 11
P. Kumaresan, C. Turner (1965)
Effect of Graded Levels of Insulin on Feed Consumption in Normal Female Rats.∗Proceedings of the Society for Experimental Biology and Medicine, 120
F. Hausberger, B. Hausberger (1958)
Effect of insulin and cortisone on weight gain, protein and fat content of rats.The American journal of physiology, 193 3
(1965)
Localized intraperi toneal action of insulin on ra t diaphragm and epididymal adipose tissue in r ive
C. Hollenberg, A. Vost, R. Patten (1970)
Regulation of adipose mass: control of fat cell development and lipid content.Recent progress in hormone research, 26
I. Novotný (1968)
pH changes during splitting of ATP in skeletal and cardiac muscle extracts and microsomes.Physiologia Bohemoslovaca, 17 6
E. Masters (1970)
Mitotic activity in cultured brown fat cells.Experimental cell research, 59 2
L. Younger, J. King, D. Steiner (1966)
Hepatic proliferative response to insulin in severe alloxan diabetes.Cancer research, 26 7
T. Braun, L. Kazdová, P. Fábry, Z. Lojda, V. Hromadkova (1968)
Meal eating and refeeding after a single fast as a stimulus for increasing the number of fat cells in abdominal adipose tissue of rats.Metabolism: clinical and experimental, 17 9
G. Haba, G. Cooper, Virginia Elting (1966)
HORMONAL REQUIREMENTS FOR MYOGENESIS OF STRIATED MUSCLE IN VITRO: INSULIN AND SOMATOTROPIN*Proceedings of the National Academy of Sciences of the United States of America, 56
C. Chlouverakis, E. Dade, R. Batt (1970)
Glucose tolerance and time sequence of adiposity, hyperinsulinemia and hyperglycemia in obese-hyperglycemic mice (obob).Metabolism: clinical and experimental, 19 9
(1968)
1 % egulation of DNA synthesis in fat cells and stromal elements from rat adipose tissue
M. Rodbell (1964)
METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS.The Journal of biological chemistry, 239
L. Baugnet-Mahieu, R. Goutier (1972)
Reutilization of labelled-thymidine and -iododeoxyuridine for nuclear and mitochondrial DNA synthesis in regenerating rat liver.Archives internationales de physiologie et de biochimie, 80 2
Jules Hirsch, Jules Hirsch, Paul Han, Paul Han (1969)
Cellularity of rat adipose tissue: effects of growth, starvation, and obesity.Journal of lipid research, 10 1
A. Taylor, K. McBean-Hopkins (1971)
DNA content of regenerating rat epididymal fat pads.Growth, 35 4
A. Martinsson (1969)
Hypertrophy and hyperplasia of human adipose tissue in obesity.Polskie Archiwum Medycyny Wewnetrznej, 42 3
(1970)
Mitotic ac t iv i ty in cultured brown fat cells
(1957)
Composition of adipose tissue in several forms of obesity
(1972)
Depot adi - peux m 6 scnt 6 rique du porcclet 6 rude morphologique
A. Ohneda, E. Parada, A. Eisentraut, R. Unger (1968)
Control of pancreatic glucagon secretion by glucose.Diabetes, 17
C. Esanu, S. Murakawa, G. Bray, M. Raben (1969)
DNA synthesis in human adipose tissue in vitro. I. Effect of serum and hormones.The Journal of clinical endocrinology and metabolism, 29 8
C. Esanu, G. Bray (1969)
DNA synthesis in human adipose tissue in vitro. II. Effect of obesity.The Journal of clinical endocrinology and metabolism, 29 8
P. Johnson, L. Zucker, J. Cruce, J. Hirsch (1971)
Cellularity of adipose depots in the genetically obese Zucker rat.Journal of lipid research, 12 6
M. Girolamo, Skinner Ns, H. Hanley, RG Sachs (1971)
Relationship of adipose tissue blood flow to fat cell size and number.The American journal of physiology, 220 4
G. Schmidt, S. Thannhauser (1945)
A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues.The Journal of biological chemistry, 161
(1968)
Age depenee of nuclear content of ra t adipose cells
(1968)
Kwas dezoksyrybonu - kleinowy mitochondriaeh
L. Salans, M. Zarnowski, R. Segal (1972)
Effect of insulin upon the cellular character of rat adipose tissue.Journal of lipid research, 13 5
W. Schneider (1957)
[99] Determination of nucleic acids in tissues by pentose analysisMethods in Enzymology, 3
N. Brière, H. Isler (1966)
Deoxyribonucleic acid labelling after tritiated thymidine injection.Canadian journal of physiology and pharmacology, 44 3
L. Herberg, F. Gries, C. Hesse-Wortmann (1970)
Effect of weight and cell size on hormone-induced lipolysis in New Zealand obese mice and American obese hyperglycemic micceDiabetologia, 6
A. Angel, H. Sheldon (1965)
ADIPOSE CELL ORGANELLES: ISOLATION, MORPHOLOGY AND POSSIBLE RELATION TO INTRACELLULAR LIPID TRANSPORT *Annals of the New York Academy of Sciences, 131
A. Fleck, H. Munro (1962)
The precision of ultraviolet absorption measurements in the Schmidt-Thannhauser procedure for nucleic acid estimation.Biochimica et biophysica acta, 55
L. Napolitano (1965)
OBSERVATIONS ON THE FINE STRUCTURE OF ADIPOSE CELLS *Annals of the New York Academy of Sciences, 131
K. Takebe, H. Kunita, S. Sawano, Y. Horiuchi, K. Mashimo (1969)
Circadian rhythms of plasma growth hormone and cortisol after insulin.The Journal of clinical endocrinology and metabolism, 29 12
N. Vodovar, F. Desnoyers, J. Flanzy (1972)
DÉPÔT ADIPEUX MÉSENTÉRIQUE DU PORCELET. ÉTUDE MORPHOLOGIQUEAnnales De Biologie Animale Biochimie Biophysique, 12
(1970)
Diabetes mellitus bei Fettsucht
L. Kazdová, T. Braun, P. Fábry (1967)
Increased DNA synthesis in epididymal adipose tissue of rats refed after a single fast.Metabolism: clinical and experimental, 16 12
O. Rafaelsen (1964)
GLYCOGEN CONTENT OF RAT DIAPHRAGM AFTER INTRAPERITONEAL INJECTION OF INSULIN AND OTHER HORMONES.Acta physiologica Scandinavica, 61
R. Luft, E. Cerasi, L. Madison, U. Euler, L. Casa, A. Roovete (1966)
Effect of a small decrease in blood-glucose on plasma-growth-hormone and urinary excretion of catecholamines in man.Lancet, 2 7457
J. Knittle, J. Hirsch (1968)
Effect of early nutrition on the development of rat epididymal fat pads: cellularity and metabolism.The Journal of clinical investigation, 47 9
W. Steele, N. Okamura, H. Busch (1964)
PREVENTION OF LOSS OF RNA, DNA AND PROTEIN INTO LIPID SOLVENTS.Biochimica et biophysica acta, 87
(1969)
Cellularity of ra t adipose tissue: Effects of growth, s tarvat ion and obesity
R. Turkington (1968)
Hormone-induced synthesis of DNA by mammary gland in vitro.Endocrinology, 82 3
W. Salmon, M. DuVall, E. Thompson (1968)
Stimulation by insulin in vitro of incorporation of (35S)sulfate and (14C)leucine into protein-polysaccharide complexes, (3H)uridine into RNA, and (3H)thymidine into DNA of costal cartilage from hypophysectomized rats.Endocrinology, 82 3
L. Kazdová, A. Vrána (1970)
INSULIN AND ADIPOSE TISSUE CELLULARITYHormone and Metabolic Research, 2
(1970)
Insulin and fattening in the genetically obese hyperlipemic rat " Fat ty "
C. Pilgrim (1971)
DNA synthesis and differentiation in developing white adipose tissue.Developmental biology, 26 1
K. Asplund (1972)
Effects of postnatal feeding on the functional maturation of pancreatic islet B-cells of neonatal ratsDiabetologia, 8
P. Mazhuga, A. Zhitnikov, L. Kharchuk (1970)
Differentiation and reproduction of cells in chondrogenesis.Anatomischer Anzeiger, 126 2
O. Rafaelsen, V. Lauris, A. Renold (1965)
Localized Intraperitoneal Action of Insulin on Rat Diaphragm and Epididymal Adipose Tissue in VivoDiabetes, 14
125 10 10 1 1 L. Kazdová P. Fábry A. Vrána Research Centre of Metabolism and Nutrition of the Institute for Clinical and Experimental Medicine Prague Czechoslovakia Summary The effect of insulin in vivo on the proliferation and cellularity of epididymal adipose tissue of growing rats was investigated. Following the intraperitoneal administration of small amounts of insulin (500 μU/ rat, twice a day), which did not influence the blood sugar level and food intake, it was found that repeated administration of insulin for 48–72 h leads in adipose tissue to an enhanced incorporation of 14 C-2-thymidine into DNA and to an increase of the total amount of DNA and RNA in the fat body. The enhanced DNA synthesis in adipose tissue of insulin-treated rats was marked in nuclear DNA and absent in mitochondrial DNA. After fractionation of adipose tissue by collagenase an enhanced DNA synthesis was found in the fraction of adipose and stromavascular cells. Morphological examination of adipose tissue of insulin-treated rats revealed cells in the phase of mitotic division and an increased ratio of fat cells of smaller size. Calculation of the number of cells in the epididymal fat body revealed that, after administration of insulin, the number of adipose and stromavascular cells increased.
Diabetologia – Springer Journals
Published: Feb 1, 1974
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.