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Toxicology Investigations Effect of Oral Administration of Aqueous Whole Extract of Cassytha Filiformis on Haematograms and Plasma Biochemical Parameters in Rats a a b Hausatu M. Babayi, B.Tech , Joseph, J. I. Udeme Prof , Joseph A. Abalaka Prof , c d d d Joseph I. Okogun Prof , O. A. Salawu, Ph.D , David D. Akumka MSc , Adamu, HND , d d d Sunday S. Zarma, OND , Bulus B. Adzu MSc , Sabo S. Abdulmumuni BSc , Kolo Ibrahime, e f d Baba B. Elisha HND , Samuel S. Zakariys, HN , Uford S. Inyang, PhD Department of Microbiology Department of Biochemistry, Federal University of Technology, Minna, Niger State, Nigeria Department of Medicinal Plant Research and Traditional Medicine Department of Pharmacology and Toxicology Diagnostic Clinic Animal Facility Centre, National Institute for Pharmaceutical Research and Development, Idu, Abuja ABSTRACT Introduction: We evaluated the sub-chronic toxicity of the aqueous herbal extract prepared from Cassytha filiformis and admin- istered daily for 28 days at dose levels (250, 500, and 1000 mg/kg bw) in male wistar albino rats. The LD of the aqueous extract was determined. Methods: The effects on body weights, organ weights, and certain haematological and plasma biochemical
Journal of Medical Toxicology – Springer Journals
Published: Aug 25, 2009
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