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Adv Ther (2015) 32:187–200 DOI 10.1007/s12325-015-0194-4 REVIEW Echinacea Reduces the Risk of Recurrent Respiratory Tract Infections and Complications: A Meta-Analysis of Randomized Controlled Trials • • Andreas Schapowal Peter Klein Sebastian L. Johnston To view enhanced content go to www.advancesintherapy.com Received: February 4, 2015 / Published online: March 18, 2015 Springer Healthcare 2015 Methods: MEDLINE, EMBASE, CAplus, BIOSIS, ABSTRACT CABA, AGRICOLA, TOXCENTER, SCISEARCH, Introduction: Respiratory tract infections are NAHL, and NAPRALERT were searched for common, and these infections occur frequently clinical trials that studied recurrent respiratory in children, susceptible adults, and older infections and complications on treatment with persons. The risk for recurrences and echinacea extracts in a generally healthy complications relates not only to the presence population. Two independent reviewers of viruses but also to immune function. selected randomized, placebo-controlled Therefore, modulation of the immune system studies of high methodological quality and a and antiviral interventions such as echinacea Jadad score of C4. Relative risks (RRs) with 95% might reduce the risk of recurrences and confidence intervals (CIs) were calculated possibly the development of complications. according to a fixed effect model. Results: Six clinical studies with a total of 2458 participants were included in the meta-analysis. Electronic supplementary
Advances in Therapy – Springer Journals
Published: Mar 18, 2015
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