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Designing Interventions Informed by Scientific Knowledge About Effects of Early Adversity: a Translational Neuroscience Agenda for Next-Generation Addictions Research

Designing Interventions Informed by Scientific Knowledge About Effects of Early Adversity: a... In spite of extensive scientific knowledge about the neurobiological systems and neural pathways underlying addictions, only limited progress has been made to reduce the population-level incidence of addictions by using prevention and treatment programs. In this area of research, the translation of basic neuroscience of causal mechanisms to effective interventions has not been fully realized. In this article, we describe how an understanding of the effects of early adverse experiences on brain and biological development may provide new opportunities to achieve impact at scale with respect to reduction of addictions. We propose four categories of new knowledge that translational neuroscience investigations of addictions should incorporate to be successful. We then describe a translational neuroscience-informed smoking cessation intervention based on this model. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Addiction Reports Springer Journals

Designing Interventions Informed by Scientific Knowledge About Effects of Early Adversity: a Translational Neuroscience Agenda for Next-Generation Addictions Research

Current Addiction Reports , Volume 2 (4) – Sep 28, 2015

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Publisher
Springer Journals
Copyright
Copyright © 2015 by Springer International Publishing AG
Subject
Medicine & Public Health; Psychiatry; Neurology
eISSN
2196-2952
DOI
10.1007/s40429-015-0071-x
Publisher site
See Article on Publisher Site

Abstract

In spite of extensive scientific knowledge about the neurobiological systems and neural pathways underlying addictions, only limited progress has been made to reduce the population-level incidence of addictions by using prevention and treatment programs. In this area of research, the translation of basic neuroscience of causal mechanisms to effective interventions has not been fully realized. In this article, we describe how an understanding of the effects of early adverse experiences on brain and biological development may provide new opportunities to achieve impact at scale with respect to reduction of addictions. We propose four categories of new knowledge that translational neuroscience investigations of addictions should incorporate to be successful. We then describe a translational neuroscience-informed smoking cessation intervention based on this model.

Journal

Current Addiction ReportsSpringer Journals

Published: Sep 28, 2015

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