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E.C. Oeke, H.W. Dehne, F. Schonbeck, A. Weber (1994)
Crop Production and Crop Protection: Estimated Losses in Major Food and Cash Crops
Antimicrobial peptides (AMPs) are natural antibiotics produced by all living organisms to fight pathogens. They are important effector molecules of the immune system both in animals and plants. AMPs are diverse in structure and mode of action. Based on the homology of amino acid sequences and 3D structures several AMP families have been distinguished. They are defensins, thionins, lipid transfer proteins, hevein- and knottin-like peptides, and cyclotides. AMPs display broad-spectrum antimicrobial activity and thus show promise for the development of disease-resistant crops by genetic engineering and for the production of new-generation drugs. In this paper, the properties of the main AMP families (defensins and hevein-like peptides) and of new 4-Cys plant AMP family are reviewed.
Russian Journal of Bioorganic Chemistry – Springer Journals
Published: Jan 28, 2012
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