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- Publisher
- Springer Journals
- Copyright
- Copyright © 2006 by Springer Science+Business Media, Inc.
- Subject
- Biomedicine; Biomedicine general; Laboratory Medicine; Internal Medicine; Pathology; Cell Biology
- ISSN
- 0007-4888
- eISSN
- 1573-8221
- DOI
- 10.1007/s10517-006-0407-6
- Publisher site
- See Article on Publisher Site
Abstract
Comparative analysis of the expression of some surface markers of human bone marrow mesenchymal stem cells, umbilical fibroblast-like cells, and skin fibroblasts was carried out by the flow cytofluorometry method. Mesenchymal stem cells and umbilical fibroblast-like cells were similar by the levels of expression of the main histocompatibility complex antigens, adhesion molecules, and some growth factor receptors. The profile of skin fibroblast surface antigens was characterized by higher expression of the markers typical of differentiated cells. The results prove the possibility of using umbilical fibroblast-like cells as an alternative source of mesenchymal stem cells for cell replacement therapy.
Journal
Bulletin of Experimental Biology and Medicine – Springer Journals
Published: Jan 24, 2006