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Cortico-cortical projections in mouse visual cortex are functionally target specific

Cortico-cortical projections in mouse visual cortex are functionally target specific Tuning of neurons in higher visual cortices is less diverse than in primary visual cortex (V1), but the mechanisms underlying this specialization are unknown. In this paper, Glickfeld and colleagues used two-photon imaging in awake mice to measure the visual responses of boutons from V1 projection neurons in the higher visual areas and found that bouton tunings matched the preference of their target areas. These findings suggest that inter-areal visual stimulus feature segregation occurs via the target-specific routing of visual information as it ascends the cortical hierarchy. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Neuroscience Springer Journals

Cortico-cortical projections in mouse visual cortex are functionally target specific

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References (60)

Publisher
Springer Journals
Copyright
Copyright © 2013 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
Subject
Biomedicine; Biomedicine, general; Neurosciences; Behavioral Sciences; Biological Techniques; Neurobiology; Animal Genetics and Genomics
ISSN
1097-6256
eISSN
1546-1726
DOI
10.1038/nn.3300
Publisher site
See Article on Publisher Site

Abstract

Tuning of neurons in higher visual cortices is less diverse than in primary visual cortex (V1), but the mechanisms underlying this specialization are unknown. In this paper, Glickfeld and colleagues used two-photon imaging in awake mice to measure the visual responses of boutons from V1 projection neurons in the higher visual areas and found that bouton tunings matched the preference of their target areas. These findings suggest that inter-areal visual stimulus feature segregation occurs via the target-specific routing of visual information as it ascends the cortical hierarchy.

Journal

Nature NeuroscienceSpringer Journals

Published: Jan 6, 2013

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