To study the histological differences between a muscle flap and a musculoperitoneal flap used as a urinary bladder wall substitute, we prospectively studied these flaps in 24 Wistar albino rats. In 12 rats a rectus abdominis muscle flap including the overlying peritoneum (RAMP flap) was sutured into a surgical defect of the bladder wall. The rectus abdominis muscle flap was interposed without peritoneum (RAM flap) in the other 12 rats. The animals were killed on postoperative day 6 (6 RAMP flaps and 6 RAM flaps) and day 90 (5 RAMP flaps and 5 RAM flaps) to obtain early and late histological results. The 2 remaining rats (1 RAMP flap and 1 RAM flap) died before 90 days. Partial resurfacing of the flaps’ muscle surface with urothelium was observed on the sixth postoperative day in both the RAMP and the RAM group. At that time, no significant histological difference in the urothelium was observed between the RAMP and the RAM flaps. After 90 days, resurfacing with urothelium was complete in both groups. We concluded that a urothelium or peritoneum lining is not needed to protect a muscle flap against contact with urine. Histologically, the presence of peritoneum in the early postoperative period seems to have had a positive effect on the quality of neo-urothelium.
European Journal of Plastic Surgery – Springer Journals
Published: Oct 1, 2004
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera