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Chemistry of Natural Compounds, Vol. 44, No. 4, 2008 1* 1 F. Matloubi Moghddam, M. Moridi Farimani, UDC 547.972 1 1 2 S. Taheri, M. Tafazoli, and G. Amin Salvia is an important genus consisting of ca. 700 species in the family Lamiaceae. In Iran, about 56 species of Salvia are growing naturally. Salvia macrosiphon Boiss is an endemic species of Iran, which is widely distributed in the west and center of Iran. This plant has been used in folk medicine as laxative for treatment of sore throat and cough. Aerial parts of this plant were collected from Doroud, Lorestan province, Iran in August 2003 at an altitude of 1550 m. Exudative flavonoids of this plant have been investigated and seven flavonoids from apigenin and luteolin derivatives were isolated [1]. The air-dried aerial parts (960 g) of S. macrosiphon were extracted with Me O at room temperature for 3 days. The extract was evaporated to dryness and the residue was column chromatographed (kieselgel 60, 70–230 mesh) with increasing polarity of petroleum ether-EtOAc and then EtOAc–MeOH. The fraction eluted with petrol–EtOAc (70:30) was subjected to another column chromatography, and elution with petrol–EtOAc (7:1) yielded compound 1 (32 mg) as colorless
Chemistry of Natural Compounds – Springer Journals
Published: Oct 30, 2008
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