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Breast phantom design for X-ray phase-contrast imaging

Breast phantom design for X-ray phase-contrast imaging Purpose Breast cancer is one of the most diffuse diseases and its incidence rate is increasing. Mammography is the gold standard exam for screening breast cancer. Nevertheless, to provide better conditions for visualization and detection of tumors, in particular to young women, techniques exploiting the X-ray phase contrast to generate images have been studied and proposed for clinical use. As every imaging modality clinically implemented, the capabilities and limitations of an X-ray phase-contrast system dedicated to breast imaging should be evaluated by a phantom. Although for mammography, there are several commercial phantoms, for tomographic X-ray phase-contrast imaging systems dedicated to breast screening, they are absent. Therefore, this study aimed to design a breast phantom for application in phase-contrast computed tomography (PC-CT) imaging. Methods A breast phantom dedicated to X-ray phase-contrast imaging was designed. The phantom has a cylindrical shape and is composed by PMMA, to mimic the breast of a young woman, with some inserts filled with tissue substitutes to normal and pathological breast tissues, such as ethanol and glycerol. These materials were chosen due to the similarity in the attenuation and scattering properties of normal and pathological human breast tissues. Results A comparison between tomographic X-ray absorption imaging http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Biomedical Engineering Springer Journals

Breast phantom design for X-ray phase-contrast imaging

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Publisher
Springer Journals
Copyright
Copyright © 2019 by Sociedade Brasileira de Engenharia Biomedica
Subject
Engineering; Biomedical Engineering and Bioengineering; Biomaterials; Biomedical Engineering/Biotechnology
ISSN
2446-4732
eISSN
2446-4740
DOI
10.1007/s42600-019-00004-3
Publisher site
See Article on Publisher Site

Abstract

Purpose Breast cancer is one of the most diffuse diseases and its incidence rate is increasing. Mammography is the gold standard exam for screening breast cancer. Nevertheless, to provide better conditions for visualization and detection of tumors, in particular to young women, techniques exploiting the X-ray phase contrast to generate images have been studied and proposed for clinical use. As every imaging modality clinically implemented, the capabilities and limitations of an X-ray phase-contrast system dedicated to breast imaging should be evaluated by a phantom. Although for mammography, there are several commercial phantoms, for tomographic X-ray phase-contrast imaging systems dedicated to breast screening, they are absent. Therefore, this study aimed to design a breast phantom for application in phase-contrast computed tomography (PC-CT) imaging. Methods A breast phantom dedicated to X-ray phase-contrast imaging was designed. The phantom has a cylindrical shape and is composed by PMMA, to mimic the breast of a young woman, with some inserts filled with tissue substitutes to normal and pathological breast tissues, such as ethanol and glycerol. These materials were chosen due to the similarity in the attenuation and scattering properties of normal and pathological human breast tissues. Results A comparison between tomographic X-ray absorption imaging

Journal

Research on Biomedical Engineering – Springer Journals

Published: Mar 7, 2019

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