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Breast Cancer-Related Lymphedema: a Review of Risk Factors, Radiation Therapy Contribution, and Management Strategies

Breast Cancer-Related Lymphedema: a Review of Risk Factors, Radiation Therapy Contribution, and... Purpose of ReviewIn recent years, breast cancer-related lymphedema (BCRL), which affects one in five patients treated for breast cancer (BC), has garnered increasing interest by clinicians and researchers as BC survival rates improve and survivorship issues become increasingly imperative. This review represents an overview of the literature for BCRL risk factors, such as radiation therapy (RT), screening, and treatment.Recent FindingsRisk factors with strong evidence include axillary surgery, regional lymph node radiation, elevated body mass index, cellulitis, and subclinical edema. Neoadjuvant and taxane-based chemotherapy, trastuzumab, breast reconstruction, RT field design, and genetic susceptibility are emerging as potentially influencing BCRL risk.SummaryComprehensive BCRL care necessitates a multidisciplinary team that coordinates BC treatment, educates patients, and vigilantly screens them throughout survivorship. Providers should be knowledgeable of BCRL risk factors and individualize patient education. Universal diagnostic criteria using relative change from baseline and consistently incorporating baseline measurements are imperative. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Breast Cancer Reports Springer Journals

Breast Cancer-Related Lymphedema: a Review of Risk Factors, Radiation Therapy Contribution, and Management Strategies

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Publisher
Springer Journals
Copyright
Copyright © Springer Science+Business Media, LLC, part of Springer Nature 2020
ISSN
1943-4588
eISSN
1943-4596
DOI
10.1007/s12609-020-00387-8
Publisher site
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Abstract

Purpose of ReviewIn recent years, breast cancer-related lymphedema (BCRL), which affects one in five patients treated for breast cancer (BC), has garnered increasing interest by clinicians and researchers as BC survival rates improve and survivorship issues become increasingly imperative. This review represents an overview of the literature for BCRL risk factors, such as radiation therapy (RT), screening, and treatment.Recent FindingsRisk factors with strong evidence include axillary surgery, regional lymph node radiation, elevated body mass index, cellulitis, and subclinical edema. Neoadjuvant and taxane-based chemotherapy, trastuzumab, breast reconstruction, RT field design, and genetic susceptibility are emerging as potentially influencing BCRL risk.SummaryComprehensive BCRL care necessitates a multidisciplinary team that coordinates BC treatment, educates patients, and vigilantly screens them throughout survivorship. Providers should be knowledgeable of BCRL risk factors and individualize patient education. Universal diagnostic criteria using relative change from baseline and consistently incorporating baseline measurements are imperative.

Journal

Current Breast Cancer Reports – Springer Journals

Published: Oct 24, 2020

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