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/lp/springer-journals/bisphenol-a-environmental-exposure-and-the-detrimental-effects-on-JQFdWgd1t4
- Publisher
- Springer Journals
- Copyright
- Copyright © 2015 by The Author(s)
- Subject
- Medicine & Public Health; Medicine/Public Health, general; Endocrinology; Metabolic Diseases
- eISSN
- 1720-8386
- DOI
- 10.1007/s40618-015-0336-1
- pmid
- 26105974
- Publisher site
- See Article on Publisher Site
Abstract
In the last decades, many reports have focused the attention on deleterious effects of novel environmental chemical compounds, including bisphenol A (BPA), on human health. BPA, a common and widely chemical contaminant acting as endocrine disruptor, accumulates in adipose tissue and may affect adipocyte metabolic and inflammatory functions. BPA, at low chronic doses, is now considered as an obesogen compound, and might contribute to the rise of metabolic syndrome, visceral adiposity and diabetes epidemics. The BPA worldwide presence in the environment is responsible for chronic exposure during vulnerable periods, such as foetal and neonatal life. The BPA source of contamination can occur via food, beverage, wastewater, air, dust and soil. BPA, as lipophilic compound, may accumulate into the adipose tissue already during foetal life and may affect adulthood health, through adverse effects on the growth and development of organs and tissues. Thus, based on several studies, it would be crucial to consider further actions aimed to refine risk assessment at least in vulnerable population, such as foetuses, infants and young children, to prevent metabolic diseases and obesity.
Journal
Journal of Endocrinological Investigation – Springer Journals
Published: Jun 24, 2015
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