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Astaxanthin increases choroidal blood flow velocity

Astaxanthin increases choroidal blood flow velocity Graefes Arch Clin Exp Ophthalmol (2012) 250:239–245 DOI 10.1007/s00417-011-1843-1 BASIC SCIENCE Michiyuki Saito & Kazuhiko Yoshida & Wataru Saito & Akio Fujiya & Kazuhiro Ohgami & Nobuyoshi Kitaichi & Hiroki Tsukahara & Susumu Ishida & Shigeaki Ohno Received: 4 January 2011 /Revised: 7 August 2011 /Accepted: 3 October 2011 /Published online: 10 November 2011 Springer-Verlag 2011 Abstract rate (SBR), which is a quantitative index of relative blood Purpose Previous studies have reported that astaxanthin flow velocity. (AXT) has antioxidative and anti-inflammatory effects in Results A significant increase of the macular SBR was seen addition to its ability to shorten blood transit times. As laser 4 weeks after AXT ingestion when compared to the pre- speckle flowgraphy (LSFG) can noninvasively visualize the ingestion values (Wilcoxon signed-rank test, P=0.018). In hemodynamics of the choroidal circulation, we used the contrast, no statistical difference in the macular SBR was technique to evaluate whether continuous ingestion of detected in the placebo group (Friedman test, P=0.598). No 12 mg of AXT per day could increase quantitative blood subjective or objective adverse events were found after the flow velocity. 12-mg AXT ingestion. Methods In this randomized, double-blind, placebo- Conclusions Results suggest that administration of AXT controlled http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Graefe's Archive for Clinical and Experimental Ophthalmology Springer Journals

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Publisher
Springer Journals
Copyright
Copyright © 2011 by Springer-Verlag
Subject
Medicine & Public Health; Ophthalmology
ISSN
0721-832X
eISSN
1435-702X
DOI
10.1007/s00417-011-1843-1
pmid
22072378
Publisher site
See Article on Publisher Site

Abstract

Graefes Arch Clin Exp Ophthalmol (2012) 250:239–245 DOI 10.1007/s00417-011-1843-1 BASIC SCIENCE Michiyuki Saito & Kazuhiko Yoshida & Wataru Saito & Akio Fujiya & Kazuhiro Ohgami & Nobuyoshi Kitaichi & Hiroki Tsukahara & Susumu Ishida & Shigeaki Ohno Received: 4 January 2011 /Revised: 7 August 2011 /Accepted: 3 October 2011 /Published online: 10 November 2011 Springer-Verlag 2011 Abstract rate (SBR), which is a quantitative index of relative blood Purpose Previous studies have reported that astaxanthin flow velocity. (AXT) has antioxidative and anti-inflammatory effects in Results A significant increase of the macular SBR was seen addition to its ability to shorten blood transit times. As laser 4 weeks after AXT ingestion when compared to the pre- speckle flowgraphy (LSFG) can noninvasively visualize the ingestion values (Wilcoxon signed-rank test, P=0.018). In hemodynamics of the choroidal circulation, we used the contrast, no statistical difference in the macular SBR was technique to evaluate whether continuous ingestion of detected in the placebo group (Friedman test, P=0.598). No 12 mg of AXT per day could increase quantitative blood subjective or objective adverse events were found after the flow velocity. 12-mg AXT ingestion. Methods In this randomized, double-blind, placebo- Conclusions Results suggest that administration of AXT controlled

Journal

Graefe's Archive for Clinical and Experimental OphthalmologySpringer Journals

Published: Nov 10, 2011

References