Reactions 1680, p55 - 2 Dec 2017 Miscarriage: 19 case reports A study reviewing cases from the Japanese Adverse Drug Event Report (JADER) database identified 19 pregnant women who had miscarriage following treatment with aripiprazole (n=18) or olanzapine (n=1) [ages and routes not stated; not all indications and durations of treatments to reaction onset stated]. The women, who had schizophrenia (n=12), delusional perception and affect lability (n=1, each), received aripiprazole 3mg–30mg [frequency not stated] between 2006 and 2014, they had miscarriage between 2007 and 2014. One another woman received olanzapine [dosage not stated], who also had a miscarriage. Author comment: "In reports of miscarriage, aripiprazole was the suspected drug in 18 cases, risperidone in no cases, olanzapine in one case, and quetiapine in two cases." Sakai T, et al. Signal of Miscarriage with Aripiprazole: A Disproportionality Analysis of the Japanese Adverse Drug Event Report Database. Drug Safety 40: 1141-1146, No. 11, Nov 2017. Available from: URL: http://doi.org/10.1007/ s40264-017-0560-z - Japan 803284676 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680
Reactions Weekly – Springer Journals
Published: Dec 2, 2017
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