A new amide, zanthorhetsamide ( 1 ), along with nine known compounds ( 2–10 ) was isolated from the roots and stem barks of Zanthoxylum rhetsa . The structure was characterized by spectroscopic methods. In addition, the antibacterial activity of the isolates was evaluated. Dihydrochelerythrine ( 4 ) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively.
Archives of Pharmacal Research – Springer Journals
Published: Jul 1, 2012
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