Antibacterial compounds from Zanthoxylum rhetsa

Antibacterial compounds from Zanthoxylum rhetsa A new amide, zanthorhetsamide ( 1 ), along with nine known compounds ( 2–10 ) was isolated from the roots and stem barks of Zanthoxylum rhetsa . The structure was characterized by spectroscopic methods. In addition, the antibacterial activity of the isolates was evaluated. Dihydrochelerythrine ( 4 ) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Pharmacal Research Springer Journals

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Publisher
Springer Journals
Copyright
Copyright © 2012 by The Pharmaceutical Society of Korea and Springer Netherlands
Subject
Pharmacy; Pharmacology/Toxicology; Pharmacy
ISSN
0253-6269
eISSN
1976-3786
D.O.I.
10.1007/s12272-012-0703-9
Publisher site
See Article on Publisher Site

Abstract

A new amide, zanthorhetsamide ( 1 ), along with nine known compounds ( 2–10 ) was isolated from the roots and stem barks of Zanthoxylum rhetsa . The structure was characterized by spectroscopic methods. In addition, the antibacterial activity of the isolates was evaluated. Dihydrochelerythrine ( 4 ) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively.

Journal

Archives of Pharmacal ResearchSpringer Journals

Published: Jul 1, 2012

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