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An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis

An expression signature of phenotypic resistance to hepatocellular carcinoma identified by... Our results disclose, for the first time, a major role of oncosuppressor genes as effectors of genetic resistance to hepatocarcinogenesis. Comparative functional genomic analysis allowed discovering an evolutionarily conserved gene expression signature discriminating HCC with different propensity to progression in rat and human. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cellular Oncology Springer Journals

An expression signature of phenotypic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis

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References (48)

Publisher
Springer Journals
Copyright
Copyright © 2012 by International Society for Cellular Oncology
Subject
Biomedicine; Oncology; Pathology; Biomedicine general; Cancer Research
ISSN
2211-3428
eISSN
2211-3436
DOI
10.1007/s13402-011-0067-z
pmid
22434528
Publisher site
See Article on Publisher Site

Abstract

Our results disclose, for the first time, a major role of oncosuppressor genes as effectors of genetic resistance to hepatocarcinogenesis. Comparative functional genomic analysis allowed discovering an evolutionarily conserved gene expression signature discriminating HCC with different propensity to progression in rat and human.

Journal

Cellular OncologySpringer Journals

Published: Mar 21, 2012

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