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The aggregative stability of nanosized particles of aluminum and magnesium oxides is considered, because they are common components of the environment. Air and water are chosen as the most probable contact media, and saline is chosen as a medium that imitates the internal human environment. It is found that, in all media, aluminum oxide particles have a lower aggregative stability and are more likely to form agglomerates than magnesium oxide particles. Nanosized particles of magnesium oxide and aluminum in the internal media of the human body tend to form nanosized clusters connected through liquid bridges; they are not stable; i.e., nanoscale particles can move in the form of a cluster and, in the medium of the target organ, they disintegrate into particles and act as a nanoscale material. The aggregative stability of nanosized particles is determined by the material of the particles, their size, and the distance between them, while it dynamically changes during the transition from the external environment to the internal environments of the body and at different stages of metabolism, which proves the need to take into account the physical interaction of particles in different environments to assess their toxicity.
Theoretical Foundations of Chemical Engineering – Springer Journals
Published: Jul 29, 2021
Keywords: nanosized particles; aggregative stability; dispersed phase; aqueous solutions; saline
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