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Activated partial thromboplastin time sensitivity to lupus anticoagulant in a patient with transient arthritis and lupus anticoagulant-hypoprothrombinemia syndrome

Activated partial thromboplastin time sensitivity to lupus anticoagulant in a patient with... Ann Hematol (2015) 94:713–715 DOI 10.1007/s00277-014-2245-3 LETTER TO THE EDITOR Activated partial thromboplastin time sensitivity to lupus anticoagulant in a patient with transient arthritis and lupus anticoagulant-hypoprothrombinemia syndrome Laetitia Mauge & Amélie Passeron & Martine Alhenc-Gelas & Jacques Pouchot & Luc Darnige Received: 10 September 2014 /Accepted: 26 October 2014 /Published online: 9 November 2014 Springer-Verlag Berlin Heidelberg 2014 (Trinity Biotech, Ireland) and dilute Russell venom viper Dear Editor, A 23-year-old man presented with a five-day history of time (dRVVT) using LA1LA2 reagents (Siemens, Ger- high fever and severe hip pain. Clinical examination many). The phospholipid dependence was confirmed by evidenced hip arthritis and a joint effusion, while the positive phospholipid-neutralizing assays for both tests patient was treated by antibiotics for pneumonia. C- with a dRVVT screen/confirm ratio at 1.77 and a ratio of reactive protein level was 33.4 mg/l; cell blood count aPTT with silica (LA sensitive reagent)/KPTT (LA showed only a mild thrombocytopenia (133 G/l). Pro- unsensitive reagent) at 1.4. Anti-cardiolipin (aCL), thrombin time and activated partial thromboplastin time anti-β2GPI (aβ2GPI) and aPT IgG and IgM were (aPTT) with kaolin (KPTT) were both prolonged; throm- searched for by using commercial ELISAs (Orgentec bin clotting time was normal. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Hematology Springer Journals

Activated partial thromboplastin time sensitivity to lupus anticoagulant in a patient with transient arthritis and lupus anticoagulant-hypoprothrombinemia syndrome

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References (14)

Publisher
Springer Journals
Copyright
Copyright © 2015 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Hematology; Oncology
ISSN
0939-5555
eISSN
1432-0584
DOI
10.1007/s00277-014-2245-3
pmid
25380995
Publisher site
See Article on Publisher Site

Abstract

Ann Hematol (2015) 94:713–715 DOI 10.1007/s00277-014-2245-3 LETTER TO THE EDITOR Activated partial thromboplastin time sensitivity to lupus anticoagulant in a patient with transient arthritis and lupus anticoagulant-hypoprothrombinemia syndrome Laetitia Mauge & Amélie Passeron & Martine Alhenc-Gelas & Jacques Pouchot & Luc Darnige Received: 10 September 2014 /Accepted: 26 October 2014 /Published online: 9 November 2014 Springer-Verlag Berlin Heidelberg 2014 (Trinity Biotech, Ireland) and dilute Russell venom viper Dear Editor, A 23-year-old man presented with a five-day history of time (dRVVT) using LA1LA2 reagents (Siemens, Ger- high fever and severe hip pain. Clinical examination many). The phospholipid dependence was confirmed by evidenced hip arthritis and a joint effusion, while the positive phospholipid-neutralizing assays for both tests patient was treated by antibiotics for pneumonia. C- with a dRVVT screen/confirm ratio at 1.77 and a ratio of reactive protein level was 33.4 mg/l; cell blood count aPTT with silica (LA sensitive reagent)/KPTT (LA showed only a mild thrombocytopenia (133 G/l). Pro- unsensitive reagent) at 1.4. Anti-cardiolipin (aCL), thrombin time and activated partial thromboplastin time anti-β2GPI (aβ2GPI) and aPT IgG and IgM were (aPTT) with kaolin (KPTT) were both prolonged; throm- searched for by using commercial ELISAs (Orgentec bin clotting time was normal.

Journal

Annals of Hematology – Springer Journals

Published: Apr 1, 2015

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