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A-Z of Neurological PracticeB

A-Z of Neurological Practice: B [Balo’s concentric sclerosis is a rare form of demyelinating disease, characterized by concentric alternating bands of myelin destruction and preservation within the cerebral hemispheres. Originally a pathological diagnosis, this appearance has also been documented antemortem using MRI: lesions show a hypointense center and intermediate rings, which enhance with gadolinium, and hyperintense inner and outer rings. Lesions that have this appearance microscopically occur in typical multiple sclerosis (“type 3” lesions). Occasionally, patients present with a monophasic or relapsing–remitting syndrome of epileptic seizures or cortical deficits and, on imaging, are found to have a single, or a few large Balo’s-type lesions; it is not clear whether this is an unsual form of multiple sclerosis or a distinct ­disorder. There is no consensus on the treatment for such patients.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A-Z of Neurological PracticeB

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Publisher
Springer London
Copyright
© Springer-Verlag London Limited 2011
ISBN
978-1-84882-993-0
Pages
55 –86
DOI
10.1007/978-1-84882-994-7_2
Publisher site
See Chapter on Publisher Site

Abstract

[Balo’s concentric sclerosis is a rare form of demyelinating disease, characterized by concentric alternating bands of myelin destruction and preservation within the cerebral hemispheres. Originally a pathological diagnosis, this appearance has also been documented antemortem using MRI: lesions show a hypointense center and intermediate rings, which enhance with gadolinium, and hyperintense inner and outer rings. Lesions that have this appearance microscopically occur in typical multiple sclerosis (“type 3” lesions). Occasionally, patients present with a monophasic or relapsing–remitting syndrome of epileptic seizures or cortical deficits and, on imaging, are found to have a single, or a few large Balo’s-type lesions; it is not clear whether this is an unsual form of multiple sclerosis or a distinct ­disorder. There is no consensus on the treatment for such patients.]

Published: Sep 22, 2010

Keywords: Benign Paroxysmal Positional Vertigo; Critical Illness Polyneuropathy; Burning Mouth Syndrome; Miller Fisher Syndrome; Brain Stem Death

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