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A Practical Guide to Skin CancerCutaneous Lymphomas

A Practical Guide to Skin Cancer: Cutaneous Lymphomas [Cutaneous B-cell and T-cell lymphomas are distinct subtypes of non-Hodgkin lymphoma (NHL). They are cancers of lymphocytes that primarily involve the skin, the most common single-organ location of extranodal NHL (Groves et al., J Natl Cancer Inst. 2000;92(15):1240–1251). Cutaneous lymphomas may remain limited to the skin for long periods of time but can spread to blood, lymph nodes, and viscera in cases of advanced disease. Cutaneous T-cell lymphomas (CTCL), involving malignant clonal T cells that present primarily in the skin, comprise more than 75% of all primary cutaneous lymphomas (Willemze et al., Blood. 2005;105(10):3768–3785). CTCL includes variants with indolent, aggressive, and variable clinical behavior, with mycosis fungoides (MF) and Sézary syndrome (SS) together comprising more than 50% of all CTCLs (Willemze et al., Blood. 2005;105(10):3768–3785). The second most common type of CTCL, CD30+ lymphoproliferative disorders, comprises 20% of all cutaneous lymphomas. Cutaneous B-cell lymphoma (CBCL) is less common and often presents as indolent disease.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

A Practical Guide to Skin CancerCutaneous Lymphomas

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Publisher
Springer International Publishing
Copyright
© Springer International Publishing AG, part of Springer Nature 2018
ISBN
978-3-319-74901-3
Pages
155 –187
DOI
10.1007/978-3-319-74903-7_8
Publisher site
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Abstract

[Cutaneous B-cell and T-cell lymphomas are distinct subtypes of non-Hodgkin lymphoma (NHL). They are cancers of lymphocytes that primarily involve the skin, the most common single-organ location of extranodal NHL (Groves et al., J Natl Cancer Inst. 2000;92(15):1240–1251). Cutaneous lymphomas may remain limited to the skin for long periods of time but can spread to blood, lymph nodes, and viscera in cases of advanced disease. Cutaneous T-cell lymphomas (CTCL), involving malignant clonal T cells that present primarily in the skin, comprise more than 75% of all primary cutaneous lymphomas (Willemze et al., Blood. 2005;105(10):3768–3785). CTCL includes variants with indolent, aggressive, and variable clinical behavior, with mycosis fungoides (MF) and Sézary syndrome (SS) together comprising more than 50% of all CTCLs (Willemze et al., Blood. 2005;105(10):3768–3785). The second most common type of CTCL, CD30+ lymphoproliferative disorders, comprises 20% of all cutaneous lymphomas. Cutaneous B-cell lymphoma (CBCL) is less common and often presents as indolent disease.]

Published: May 15, 2018

Keywords: Cutaneous T-cell lymphoma; Mycosis fungoides; Sézary syndrome; Folliculotropic mycosis fungoides; Pagetoid reticulosis (Woringer-Kolopp); Granulomatous slack skin; Hypopigmented mycosis fungoides; Cutaneous B-cell lymphoma; Primary cutaneous follicular center lymphoma; Primary cutaneous marginal zone B-cell lymphoma; Primary cutaneous large B-cell lymphoma (PCLBCL); Leg-type

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