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A clinical and experimental comparison of four anti-schizophrenic drugs

A clinical and experimental comparison of four anti-schizophrenic drugs Psychopharmacologi~ 1,437--449 (1960) Original Investigations Originalarbeiten Travaux originaux Drug Research Unit, Departmen~ of Psychiatry, The University of Toronto By R. L. D. W l ~ H T and W . P . KY~E (Received April 25, 1960) Increasing usage of tranquilizing drugs in recent years has been a reflection of their undoubted clinical value in the management of schizophrenia and other allied disorders. Clinicians have described these drugs, mainly from the phenothiazine and rauwolfia families, as producing "quieter, more cooperative, and more accessible patients" from those previously restless, aggressive, and hostile. Anxiety is often reduced and communication improved. Hallucinations and delusions frequently become less intense, or at least less disturbing, and better social adaptivity consequently becomes possible, often to the point of discharge from hospital. Such remissions may often be maintained on the appropriate regime of chemotherapy, and within the institution the effects of such di'ugs may be felt in the increase of numbers in open wards, and by the decrease in nursing problems generally. Efforts to maintain and further brighten this situation have resulted in a continuing supply of new drugs accompanied by a deluge of more or less valid claims for their therapeutic superiorities. These claims http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychopharmacology Springer Journals

A clinical and experimental comparison of four anti-schizophrenic drugs

Psychopharmacology , Volume 1 (6) – Nov 1, 1960

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References (6)

Publisher
Springer Journals
Copyright
Copyright © 1960 by Springer-Verlag
Subject
Biomedicine; Pharmacology/Toxicology; Psychiatry
ISSN
0033-3158
eISSN
1432-2072
DOI
10.1007/BF00429269
Publisher site
See Article on Publisher Site

Abstract

Psychopharmacologi~ 1,437--449 (1960) Original Investigations Originalarbeiten Travaux originaux Drug Research Unit, Departmen~ of Psychiatry, The University of Toronto By R. L. D. W l ~ H T and W . P . KY~E (Received April 25, 1960) Increasing usage of tranquilizing drugs in recent years has been a reflection of their undoubted clinical value in the management of schizophrenia and other allied disorders. Clinicians have described these drugs, mainly from the phenothiazine and rauwolfia families, as producing "quieter, more cooperative, and more accessible patients" from those previously restless, aggressive, and hostile. Anxiety is often reduced and communication improved. Hallucinations and delusions frequently become less intense, or at least less disturbing, and better social adaptivity consequently becomes possible, often to the point of discharge from hospital. Such remissions may often be maintained on the appropriate regime of chemotherapy, and within the institution the effects of such di'ugs may be felt in the increase of numbers in open wards, and by the decrease in nursing problems generally. Efforts to maintain and further brighten this situation have resulted in a continuing supply of new drugs accompanied by a deluge of more or less valid claims for their therapeutic superiorities. These claims

Journal

PsychopharmacologySpringer Journals

Published: Nov 1, 1960

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