Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

A Case for Antifungal Stewardship

A Case for Antifungal Stewardship Purpose of Review The expanding utilization of limited available antifungal agents has led to a pressing need to implement interventions to ensure appropriate usage. The global emergence of resistant, difficult-to-treat invasive fungal infections among the most vulnerable patient populations is a call to action to develop a multifaceted antifungal stewardship approach. Recent Findings Candida species demonstrating multi-drug resistance, including highly resistant Candida auris, are emerging threats. Azole-resistant Aspergillus fumigatus, likely initially originating in the environment, likewise presents a treatment challenge. Routine empiric and prophylactic antifungal use, though effective, further complicates this issue, with the emergence of breakthrough mold infections. Early evidence supports success with antifungal stewardship programs. Summary Broad antifungal stewardship approaches that optimize antifungal drug usage, facilitate provider education, and monitor fungal epidemiology are crucial steps to preserve the antifungal armamentarium. Future development of novel diagnostic and treatment strategies will further facilitate management of invasive fungal infections. . . . . . Keywords Antifungal stewardship Candida Aspergillus fumigatus Antifungal resistance Azole Echinocandin Introduction among physicians, pharmacists, microbiologists, and infec- tion control programs. Herein, the evolution of antifungal re- Invasive fungal infections remain a significant cause of mor- sistance as a driver to propel antifungal stewardship practice is bidity http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Fungal Infection Reports Springer Journals

A Case for Antifungal Stewardship

Current Fungal Infection Reports , Volume 12 (1) – Jan 15, 2018

Loading next page...
 
/lp/springer-journals/a-case-for-antifungal-stewardship-e9CftKlnIc

References (87)

Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Infectious Diseases; Internal Medicine; Tropical Medicine; Occupational Medicine/Industrial Medicine; Pneumology/Respiratory System
ISSN
1936-3761
eISSN
1936-377X
DOI
10.1007/s12281-018-0307-z
Publisher site
See Article on Publisher Site

Abstract

Purpose of Review The expanding utilization of limited available antifungal agents has led to a pressing need to implement interventions to ensure appropriate usage. The global emergence of resistant, difficult-to-treat invasive fungal infections among the most vulnerable patient populations is a call to action to develop a multifaceted antifungal stewardship approach. Recent Findings Candida species demonstrating multi-drug resistance, including highly resistant Candida auris, are emerging threats. Azole-resistant Aspergillus fumigatus, likely initially originating in the environment, likewise presents a treatment challenge. Routine empiric and prophylactic antifungal use, though effective, further complicates this issue, with the emergence of breakthrough mold infections. Early evidence supports success with antifungal stewardship programs. Summary Broad antifungal stewardship approaches that optimize antifungal drug usage, facilitate provider education, and monitor fungal epidemiology are crucial steps to preserve the antifungal armamentarium. Future development of novel diagnostic and treatment strategies will further facilitate management of invasive fungal infections. . . . . . Keywords Antifungal stewardship Candida Aspergillus fumigatus Antifungal resistance Azole Echinocandin Introduction among physicians, pharmacists, microbiologists, and infec- tion control programs. Herein, the evolution of antifungal re- Invasive fungal infections remain a significant cause of mor- sistance as a driver to propel antifungal stewardship practice is bidity

Journal

Current Fungal Infection ReportsSpringer Journals

Published: Jan 15, 2018

There are no references for this article.